Multichannel triple quadrupole mass spectrum array system

Abstract

The invention discloses a multichannel triple quadrupole mass spectrum array system. The multichannel triple quadrupole mass spectrum array system comprises an ion guidance system which is used to guide an ion source to a triple quadrupole mass spectrometer, and further comprises the triple quadrupole mass spectrometer which comprises a plurality of groups of triple quadrupole rods arranged in parallel and evenly distributed on peripheries of circles of the same diameter, and is used to dissociate ion currents output by the ion source into characteristic fragments after performing quality selection on the ion currents, and an ion detection system which comprises a plurality of detectors used to detect select the characteristic fragments from each group of the triple quadrupole rods. The multichannel triple quadrupole mass spectrum array system can perform synchronous detection analysis on a plurality of target molecules or a plurality of dissociation galleries of a same target molecule, which are synchronously eluted by liquid chromatography, and accordingly improve analysis flux and sensitivity and enlarges dynamic ranges in multiples for the triple quadrupole mass spectrometer.

Description

technical field [0001] The invention belongs to the technical field of analytical instruments, and in particular relates to a multi-channel triple quadrupole mass spectrometry array system capable of multi-reaction detection. Background technique [0002] Traditional biology and medicine have made great progress in the past 100 years, which has more than doubled the average life span of human beings; but they are still powerless against many complex diseases, such as diabetes, cancer and most viral diseases. Investigating its causes, these diseases are largely systemic diseases, which means that they are related to multiple organs of the body, and even the whole body. In this context, systems biology and its corresponding personalized medicine have flourished. Systems biology conducts a comprehensive analysis of all systems that make up the human body at the molecular level, such as genome, transcriptome, proteome, metabolome, etc., and collects all relevant information; co...

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Problems solved by technology

However, at present, all electrospray ion sources are only followed by a mass spectrometer detector, and the analysis throughput is limited; at the same time, the ions that pass through the multi-ion sampling interface are remixed and enter a single mass spectrometer detector, and the improvement of sensitivity is also very limited, because still Unable to get rid of the limitation of ion trap charge capacity

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