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Pain-alleviating and bacterium-resisting Chinese medicinal composition and preparation method thereof

A technology of composition and traditional Chinese medicine, which is applied in the direction of antibacterial drugs, drug combinations, pharmaceutical formulas, etc., can solve problems such as low extraction rate, influence on drug efficacy, and failure to propose active ingredients, and achieve excellent antibacterial effect, significant inhibitory effect, and antibacterial effect. obvious pain effect

Inactive Publication Date: 2014-04-23
GUANGXI WUZHOU PHARMA GRP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0018] Due to the different properties of the active ingredients in the eight-flavored medicinal materials, if the preparation methods in the above patents all use water extraction, some active ingredients cannot be extracted, or the extraction rate is low, which will affect the efficacy of the drug.

Method used

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  • Pain-alleviating and bacterium-resisting Chinese medicinal composition and preparation method thereof
  • Pain-alleviating and bacterium-resisting Chinese medicinal composition and preparation method thereof
  • Pain-alleviating and bacterium-resisting Chinese medicinal composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0068] 1) Take the following medicinal materials in parts by weight: 456g of Desmodium glabra, 302g of Corn Stigma, 228g of Shiwei, 228g of Chicken Bone Grass, 228g of Poria Cocos, 165g of Plantain, 165g of Sea Golden Sand Grass, 228g of Imperata Rhizome;

[0069] 2) Add corn silk, Desmodium sativa, Shiwei, and Jigucao with a mass-volume percentage of 0.1% sodium bicarbonate solution for extraction twice, adding sodium bicarbonate solution 20 times and 15 times the total weight of the medicinal materials respectively, Each extraction time is 4 hours and 2 hours respectively, the extracts are combined, filtered, and the filtrate is concentrated into a liquid extract;

[0070] 3) Add water to extract 2 times of Rhizoma Imperatae Cocos, Poria Cocos, Sea Golden Sand Grass, and Plantain, each time adding 12 times and 10 times the total weight of the four traditional Chinese medicines, decocting for 3 hours and 2 hours each time, and decocting together liquid, filtered, and the filt...

Embodiment 2

[0073] 1) Take the following medicinal materials in parts by weight: 456g of Desmodium glabra, 302g of Corn Stigma, 228g of Shiwei, 228g of Chicken Bone Grass, 228g of Poria Cocos, 165g of Plantain, 165g of Sea Golden Sand Grass, 228g of Imperata Rhizome;

[0074] 2) Corn silk, Desmodium radix, Shiwei, and Jigucao are extracted 3 times with sodium bicarbonate solution with a mass-volume percentage of 1%, adding 20 times, 15 times, and 10 times the total weight of the medicinal materials each time. Sodium solution, each extraction time is 4 hours, 2 hours, and 1 hour respectively, the extracts are combined, filtered, and the filtrate is concentrated into a liquid extract;

[0075] 3) Add water and extract 3 times of Imperata cocos root, Poria cocos, Sea ginseng grass, and plantain, add 12 times, 10 times, and 6 times the total weight of the four traditional Chinese medicines each time, and decoct for 3 hours and 2 hours each time , 1 hour, combine the decoction, filter, and con...

Embodiment 3

[0078] 1) Take the following medicinal materials in parts by weight: 456g of Desmodium glabra, 302g of Corn Stigma, 228g of Shiwei, 228g of Chicken Bone Grass, 228g of Poria Cocos, 165g of Plantain, 165g of Sea Golden Sand Grass, 228g of Imperata Rhizome;

[0079] 2) Corn silk, Desmodium radix, Shiwei, and Jigucao are extracted 3 times with sodium bicarbonate solution with a mass-volume percentage of 0.5%, adding 20 times, 15 times, and 10 times the total weight of the medicinal materials each time. Sodium solution, each extraction time is 3 hours, 2 hours, and 1 hour respectively, the extracts are combined, filtered, and the filtrate is concentrated into a liquid extract;

[0080] 3) Add water to extract Imperata rhizome, Poria cocos, sea ginseng grass, and plantain 3 times, add water 10 times, 8 times, and 8 times the total weight of the four traditional Chinese medicines each time, and decoct for 3 hours and 2 hours each time , 2 hours, combined the decoction, filtered, and...

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Abstract

The invention relates to a pain-alleviating and bacterium-resisting Chinese medicinal composition and a preparation method thereof. The method for preparing the Chinese medicinal composition mainly comprises the steps of preparing eight types of medicinal materials, namely snowbell-leaf tickclover herb, corn stigma, pyrrosia leaf, chickenbone herb, Indian buead, plantain herb, Japanese climbing fern spore and cogongrass rhizome; extracting the corn stigma, snowbell-leaf tickclover herb, pyrrosia leaf and chickenbone herb with an alkaline aqueous solution; extracting the cogongrass rhizome, Indian buead, Japanese climbing fern spore and plantain herb with water; finally combining liquid extracts obtained by using the two extraction methods. As proved by the results of animal pharmacological experiments and clinical tests, the Chinese medicinal composition provided by the invention has better pain-alleviating and bacterium-resisting effects than the prior art in the treatment of urinary systematic calculi.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating calculi in the urinary system, in particular to an analgesic and antibacterial traditional Chinese medicine composition and a preparation method thereof. Background technique [0002] Urinary system stones belong to the scope of "sand stranguria", "stone stranguria" and "blood stranguria" in TCM gonorrhea, mainly including 4 syndrome types: [0003] (1) Qi stagnation and blood stasis type: Symptoms include dull pain in the waist, dull pain, normal or tight pulse, and normal tongue; or sudden interruption of urination during drowning, severe pain that extends to the waist and abdomen, and the pain is relieved after the discharge of sand and stones; or Pain in the waist and flanks, which is like twisting, causing the lower abdomen, frequent attacks, pale complexion, cold sweat, nausea, accompanied by blood in the urine or yellowish urine, dark red tongue or petechiae, ecchym...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P29/00A61P31/04A61P13/04
Inventor 刘冠萍郑志远张栩颜林艳英吴赛春贤明华陈露
Owner GUANGXI WUZHOU PHARMA GRP
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