Glossy privet fruit-astragalus membranaceus effervescent preparation and preparation method thereof

An effervescent preparation, the technology of Zhenqi, which is applied in the direction of medical formula, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problems of inconvenient taking and single dosage form of Zhenqi preparations

Inactive Publication Date: 2014-04-16
GUIZHOU XINBANG PHARMACEUTICAL CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The object of the present invention is to provide an effervescent preparation of Zhenqi and its preparation method, which can solve the problem of single dosage form and inconvenient taking of the existing Zhenqi preparation, and optimize the preparation process. better curative effect

Method used

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  • Glossy privet fruit-astragalus membranaceus effervescent preparation and preparation method thereof
  • Glossy privet fruit-astragalus membranaceus effervescent preparation and preparation method thereof
  • Glossy privet fruit-astragalus membranaceus effervescent preparation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0132] Embodiment 1 of the present invention: a chastity effervescent granule, which is made of Ligustrum lucidum 35g, astragalus 70g, citric acid 20g, sodium bicarbonate 30g, mannitol 15g and micronized silica gel 3g. Add water to decoct Astragalus and Ligustrum lucidum three times, add 8 times the amount of water for the first time, decoct for 2.5 hours, add 6 times the amount of water for the second and third times, decoct for 1.5 hours, filter, and combine the filtrate; put the filtrate in Concentrate under reduced pressure at 78°C and a vacuum of 0.08Mpa to a clear paste with a relative density of 1.05 at 60°C; put mannitol into the fluidized bed granulation chamber, and then spray the clear paste in the form of a mist, and control the inlet air temperature at 165 ℃, the air outlet temperature is 80 ℃, and the medicinal powder is obtained for use; add sieved citric acid, sodium bicarbonate and micropowder silica gel, mix evenly, and put it into a dry granulator to make 40-...

Embodiment 2

[0133] Embodiment 2 of the present invention: a Zhenqi effervescent tablet, which is made of Ligustrum lucidum 25g, Astragalus 50g, tartaric acid 15g, sodium carbonate 20g, lactose 10g and micronized silica gel 1g. Add water to decoct Astragalus and Ligustrum lucidum three times, add 8 times the amount of water for the first time, decoct for 2.5 hours, add 6 times the amount of water for the second and third times, decoct for 1.5 hours, filter, and combine the filtrate; put the filtrate in Concentrate under reduced pressure at 75°C and a vacuum of 0.07Mpa to a clear paste with a relative density of 1.05 at 60°C; put lactose into the fluidized bed granulation chamber, and then spray the clear paste in the form of mist, and control the inlet air temperature at 160°C , the temperature of the air outlet is 75°C, and the medicinal powder is obtained for use; add sieved tartaric acid, sodium carbonate and micro-powdered silica gel, mix well, put it into a dry granulator to make 40-50...

Embodiment 3

[0134] Example 3 of the present invention: a chastity effervescent granule, which is made of Ligustrum lucidum 40g, astragalus 80g, tartaric acid 25g, sodium bicarbonate 35g, mannitol 10g, lactose 10g and micronized silica gel 5g. Add water to decoct Astragalus and Ligustrum lucidum three times, add 8 times the amount of water for the first time, decoct for 2.5 hours, add 6 times the amount of water for the second and third times, decoct for 1.5 hours, filter, and combine the filtrate; put the filtrate in Concentrate under reduced pressure at 80°C and a vacuum of 0.09Mpa to a clear paste with a relative density of 1.05 at 60°C; put mannitol and lactose into the fluidized bed granulation chamber, and then spray the clear paste in mist form to control the air intake The temperature is 170°C, the air outlet temperature is 90°C, and the medicinal powder is obtained for standby; add sieved tartaric acid, sodium bicarbonate and micro-powdered silica gel, mix evenly, and put it into a...

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Abstract

The invention discloses a glossy privet fruit-astragalus membranaceus effervescent preparation and a preparation method thereof. The glossy privet fruit-astragalus membranaceus effervescent preparation is prepared from 25-40 parts of glossy privet fruit, 50-80 parts of astragalus membranaceus and a proper amount of accessories, wherein the accessories include 15-25 parts of acid agent, 20-35 parts of alkaline agent, 10-20 parts of filler and 1-10 parts of a lubricant. The effervescent preparation disclosed by the invention can solve problems of an existing glossy privet fruit-astragalus membranaceus which is simple in dosage form and inconvenient to take, and optimizes a preparation process; the produced preparation is completely dissolved, rapid to become effective and better in curative effect.

Description

technical field [0001] The invention relates to a Zhenqi effervescent preparation and a preparation method thereof, belonging to the technical field of traditional Chinese medicine preparation. Background technique [0002] Zhenqi preparation is mainly composed of Astragalus membranaceus and Ligustrum lucidum. Raw astragalus is used to invigorate qi and solidify the exterior, diuresis and detoxification, while Ligustrum lucidum nourishes the liver and kidney, and has black hair. At present, the similar products produced in China are mainly Zhenqi Fuzheng Granules, which have a relatively single dosage form. This preparation can improve the immune function of the body; increase blood cells, protect bone marrow, adrenal cortex and liver functions; promote the production of interferon; cooperate with radiotherapy and chemotherapy for tumor patients, It can reduce the toxic and side effects of patients during radiotherapy and chemotherapy, and promote the recovery of normal func...

Claims

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Application Information

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IPC IPC(8): A61K36/638A61K9/46A61K47/02A61K47/04A61K47/12A61K47/26A61K47/32A61K47/34A61P37/04A61P35/00A61K47/10
Inventor 张观福
Owner GUIZHOU XINBANG PHARMACEUTICAL CO LTD
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