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Probiotics and Chinese herbal medicine compound preparation with hypoglycemic function

A technology of probiotics and Chinese herbal medicines, applied in the field of probiotics and Chinese herbal medicine compound preparations, can solve problems such as adverse reactions, achieve the effects of reducing morbidity, sufficient resources, and enhancing body immunity

Active Publication Date: 2014-03-26
NANCHANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

It is well known that there are only a few chemical drugs currently used clinically to lower blood sugar, and these drugs have certain limitations and adverse reactions.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0013] (1) Cultivate compound probiotics, lyophilize, and obtain a mixed compound probiotic comprising 4 parts of Bifidobacterium adolescentis, 4 parts of Bifidobacterium longum, 1 part of Lactobacillus plantarum and 1 part of Lactobacillus rhamnosus in parts by weight freeze-dried powder;

[0014] (2) Grinding and sieving the washed and dried Chinese herbal medicine yam, kudzu root, cinnamon, cinnamon, and medlar under sterile and dust-free conditions with a 200-400 mesh sieve;

[0015] (3) Irradiation sterilization: control the irradiation dose of 60rad, the irradiation dose rate of 240rad / min and the irradiation time of 46h for sterilization;

[0016] (4) The components are mixed according to the weight ratio of 25-30 parts of yam, 15-25 parts of kudzu root, 20-30 parts of cinnamon, 20-40 parts of medlar and 30-40 parts of probiotic freeze-dried powder.

Embodiment 2

[0018] The hypoglycemic effect of the drug was verified by in vitro experiments. The mouse pancreas was damaged by intraperitoneal injection of alloxan, thereby increasing blood sugar. Mice with a blood glucose value > 10 mM / L were considered hyperglycemic mice. Select 20 hyperglycemic mice and divide them into two groups randomly. One group is the control group, which is continuously fed with 200 μL normal saline for 30 days; the other group is the experimental group, which is continuously fed with 200 μL probiotic-Chinese herbal medicine compound 20%) for 30 days. During the whole experimental period, the body weight, food intake, water consumption, blood sugar changes and the dynamic changes of the intestinal flora of the mice between the two groups were monitored every 7 days. The results of animal experiments showed that after intragastric administration of probiotics-Chinese herbal medicine compound preparations, the body weight, food intake, and water intake of the mi...

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Abstract

The invention belongs to the field of health-care products, and particularly relates to a probiotics and Chinese herbal medicine compound preparation with a hypoglycemic function. The preparation is formed by mixing the components in parts by weight as follows: 25-30 parts of dioscorea roots, 15-25 parts of pueraria roots, 20-30 parts of cinnamon, 20-40 parts of lycium berries and 30-40 parts of freeze-dried probiotics powder, wherein probiotics comprises bacteria in percentage by weight as follows: 40% of bifidobacterium adolescentis, 40% of bifidobacterium longum, 10% of lactobacillus plantarum and 10% of lactobacillus rhamnosus. The preparation has the hypoglycemic function.

Description

technical field [0001] This product relates to the field of health care products, in particular to a probiotic Chinese herbal medicine compound preparation with the function of lowering blood sugar. Background technique [0002] Diabetes is a secretory metabolic disease caused by the interaction of genetic and environmental factors. In the past ten years, the incidence of diabetes has been on the rise, and it has become the third chronic disease that seriously threatens human health after tumors and cardiovascular diseases. According to WHO estimates, in the next 10 years, the incidence of diabetes in the world will double, and its prevention and treatment have become an important proposition in the field of medicine. It is well known that there are only a few chemical drugs currently used clinically to lower blood sugar, and these drugs have certain limitations and adverse reactions. Therefore, it is of great significance to screen out safe, reliable and hypoglycemic acti...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8945A61P3/10A61P1/00A61P37/04A23L1/29A61K35/74A23L33/00A61K35/745A61K35/747
Inventor 魏华徐锋许恒毅董素琴赖卫华
Owner NANCHANG UNIV
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