Method for reducing flow fluctuations in liquid chromatograph and infusion pump device

Abstract

The invention discloses a method for reducing flow fluctuations in a liquid chromatograph and an infusion pump device. The infusion pump device comprises a main control unit, the main control unit in control connection with a motor, the motor is in transmission connection with a cam group, and the cam group comprises a large cam and a small cam, wherein the large cam and the small cam are connected in series. The large cam and the small cam are respectively provided with a cam positioning device and drive a first plunger rod and a second plunger rod to alternately reciprocate in a first hydraulic cylinder and a second hydraulic cylinder respectively. An inlet in the first hydraulic cylinder and an outlet in the first hydraulic cylinder are respectively provided with a one-way valve, and the outlet in the first hydraulic cylinder is connected with the second hydraulic cylinder and provided with a pressure detecting device for detecting the pressure of a flowing phase in a monitoring system in real time. The cam positioning devices and the pressure detecting device are connected with the main control unit, the pressure detecting device is further connected with one input end of a comparator, and the other input end of the comparator and the output end of the comparator are both connected with the main control unit. The method for reducing the flow fluctuations in the liquid chromatograph and the infusion pump device ensure that analysis results of the liquid chromatograph are accurate and reliable.

Description

Technical field: [0001] The invention relates to the field of liquid chromatographs, in particular to a method for reducing flow fluctuations in liquid chromatographs and an infusion pump device. Background technique: [0002] Liquid chromatograph is a widely used analytical instrument, which uses the difference in physical and chemical properties of each component in the mixture to be separated to separate it in mobile phase and stationary phase to different degrees, and then conducts the separation of the separated components. In quantitative analysis, whether the flow rate of the mobile phase (solvent) is constant or not directly affects the detection results of the liquid chromatograph, so it is necessary to ensure that the infusion pump system provides a constant flow rate. [0003] When the infusion pump transports the solvent from the solvent bottle to the chromatographic column, the pressure of the solvent rises from one atmosphere to tens of MPa. The increase in pre...

AI Technical Summary

Problems solved by technology

When analyzing a variety of substances, the mobile phase needs to be replaced, and the damper is easy to cause the residue of the mobile phase, which affects the accuracy of the analysis

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