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Application of phyllanthus emblica extract in preparation of health food or cosmetics with anti-radiation and anti-aging efficacy

A technology for health-care food and emblica, applied in the field of emblica, can solve problems such as unpublished, and achieve the effects of low preparation cost, reduced cell damage, and full utilization of resources

Active Publication Date: 2014-02-19
INFINITUS (CHINA) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] At present, there is no published research on the application of emblica extract in the preparation of health food or cosmetics with anti-radiation and anti-aging effects.

Method used

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  • Application of phyllanthus emblica extract in preparation of health food or cosmetics with anti-radiation and anti-aging efficacy
  • Application of phyllanthus emblica extract in preparation of health food or cosmetics with anti-radiation and anti-aging efficacy
  • Application of phyllanthus emblica extract in preparation of health food or cosmetics with anti-radiation and anti-aging efficacy

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] The preferred preparation method of the emblica extract provided by the invention comprises the following steps:

[0047] A pre-treatment: wash the raw material emblica emblica with water, crush, sieve to 30-60 mesh, and weigh 1 kg;

[0048] B extraction: 2 times with 8-10 kg of methanol at room temperature for ultrasonic extraction, 20-40 minutes each time, filter with 500-800 mesh filter cloth, combine the filtrate, recover methanol under vacuum and decompression, and obtain B extract with a weight of 0.2-0.3 kg of raw materials ;

[0049] C extraction: Ultrasonic extraction with n-butanol equal to the weight of B extract for 30-50 minutes, filtered to obtain 0.3-0.5 kg of C extract;

[0050] D Separation of samples: C extract was diluted with 4.5-10 kg of water, filtered, loaded on two columns equipped with PIPO-02 separation material, and eluted with 0.2% (volume percentage, the same below) formic acid water 10-15 kg, separate two separation columns, wash the seco...

Embodiment 2

[0053] The preferred preparation method of the emblica extract provided by the invention comprises the following steps:

[0054] A pre-treatment: wash the raw material emblica emblica with water, crush, sieve to 30-60 mesh, and weigh 10 kg;

[0055] B extraction: 2 times with 80-100 kg of methanol ultrasonically extracted at room temperature, 20-40 minutes each time, filtered through 500-800 mesh filter cloth, combined filtrate, vacuum and decompressed to recover methanol, and obtained B extract with a weight of 2-3 kg of raw materials ;

[0056] C extraction: Ultrasonic extraction with n-butanol equal to the weight of B extract for 30-50 minutes, filtered to obtain 3-5 kg ​​of C extract;

[0057] D Separation of samples: Dilute C extract with 45-100 kg of water, filter, load the sample on two columns equipped with PIPO-02 separation material, elute 100-150 kg with 0.2% formic acid water, separate the two separation column, the second column was washed with water for 30-50 k...

Embodiment 3

[0060] The preferred preparation method of the emblica extract provided by the invention comprises the following steps:

[0061] A pre-treatment: wash the raw material emblica emblica with water, crush, sieve to 30-60 mesh, and weigh 100 kg;

[0062] B extraction: use 800-1000 kilograms of methanol to ultrasonically extract at room temperature twice, each time for 20-40 minutes, filter with a 500-800 mesh filter cloth, combine the filtrate, recover methanol under vacuum and decompression, and obtain B extract with a weight of 20-30 kilograms of raw materials ;

[0063] C extraction: Ultrasonic extraction with n-butanol equal to the weight of B extract for 30-50 minutes, filtered to obtain 30-50 kg of C extract;

[0064] D Separation of samples: Dilute C extract with 450-1000 kg of water, filter, load the sample on two columns equipped with PIPO-02 separation material, elute 1000-1500 kg with 0.2% formic acid water, separate the two separation column, the second column was wa...

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Abstract

The invention discloses application of a phyllanthus emblica extract in preparation of health food or cosmetics with anti-radiation, anti-inflammation and anti-aging efficacy, the phyllanthus emblica extract has anti-UVA (Ultra Violet A) radiation efficacy, can substantially reduce cell damage caused by UV radiation, simultaneously has an obvious inhibition effect on macrophage inflammatory factor expression, and can play anti-inflammation and anti-aging effects; the invention also illuminates, in cell and molecular level, that the phyllanthus emblica extract has anti-UV radiation and anti-aging effects. In addition, the invention also discloses a preferred preparation method of the phyllanthus emblica extract having the anti-radiation and anti-aging effects.

Description

technical field [0001] The invention belongs to the technical field of emblica, and specifically relates to the application of emblica extract in preparing health food or cosmetics with anti-radiation and anti-aging effects. technical background [0002] In recent years, active ingredients derived from plants have been increasingly used in compositions for medicinal, therapeutic, and cosmetic purposes. At present, plant emblica extract is used in various medicine and health care. [0003] Aging is a physiological phenomenon, and its physiological manifestation is the decline of the functions of various organs, leading to the occurrence of various aging diseases. And the most intuitive evidence is the aging of the skin. At the molecular level, it is manifested as cellular senescence, which is a gradual event that accompanies the aging of the body. Aging not only leads to the degradation of the body's physiological functions, but also the gradual degradation of the body's i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/97A61Q19/08A61Q17/04A23L1/30A23L33/105
Inventor 赵宏伟王一飞吴志韻袁晓唐青涛马忠华
Owner INFINITUS (CHINA) CO LTD
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