Composite chitosan dressing

A technology of chitosan and hemostatic layer, applied in the field of chitosan composite dressing, can solve the problems of restricting wound type and location, etc.

Inactive Publication Date: 2014-01-29
UNION MEDICAL SUPPLIES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although blending can improve the mechanical and chemical properties of chitosan, it also limits the type and location of the wound; U.S. Patent No. 5,597,581 discloses that chitosan and alginate are blended by wet spinning, which is worthy of hemostatic and anti-aging properties. A dressing that has mildew and antibacterial properties and can promote healing. The fluid absorption capacity of the blended dressing is 28 times its own weight
But only for chronic wounds with a lot of exudate

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] The chitosan composite dressing described in embodiment 1 is a layered material composed of a backing layer, a chitosan healing-promoting layer, a chitosan hemostatic layer and a guard. Its functional components are chitosan non-woven fabric layer and chitosan particle layer, and does not contain other functional components. When the chitosan healing-promoting layer material is chitosan non-woven fabric, its thickness is 0.3-0.4mm, and the gram weight is 40-50g / m 2 , the chitosan is chitosan prepared from chitin with a degree of deacetylation above 98%, can not absorb water and exudate, and its composition is glucosamine polymer. When the chitosan healing-promoting layer material is swollen chitosan non-woven fabric, its thickness is 0.3-0.4mm, and its gram weight is 40-50g / m 2 , can quickly absorb water and exudate, the liquid absorption is 10-20 times of its own weight, its solution pH5.5-6.5, the composition is chitosan and its hydrochloride. The chitosan hemostati...

Embodiment 2

[0026] The chitosan composite dressing described in Example 2 is a layered material made of backing layer, chitosan non-woven fabric, chitosan gauze and leaf guard. The chitosan non-woven fabric material is a non-absorbent chitosan non-woven fabric with a thickness of 0.3-0.4mm and a gram weight of 40-50g / m 2 , the chitosan is the chitosan prepared after the deacetylation degree of chitin is above 98%. In addition, when the chitosan nonwoven fabric is a swollen chitosan nonwoven fabric, the thickness is 0.3-0.4mm, and the gram weight is 40-50g / m 2, the absorption capacity is 15 times its own weight, pH5.5-6.5, the composition is chitosan and its hydrochloride. The chitosan non-woven fabric can be selected from one of non-absorbent chitosan non-woven fabric and swellable chitosan non-woven fabric, or both can be used together. Chitosan gauze is made by sticking chitosan particles on the surface of gauze through glue, with a thickness of 0.6-0.8mm, and the liquid absorption ca...

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Abstract

The invention relates to a composite chitosan dressing, and belongs to the technical field of hemostatic materials. The composite chitosan dressing is of a layered structure with a functional layer, wherein the functional layer is formed by compounding a chitosan recovery promoting layer and a chitosan hemostasis layer; the functional components of the functional layer contain no other components except for chitosan. The composite dressing plays the role by directly contacting with red blood cells and blood platelets without depending on in-vivo hemostasis mechanisms, moreover no irritability is caused, no heat is released, and the role can come into play under the condition of low body temperature. The composite chitosan dressing provided by the invention is applicable to gynaecology and obstetrics surgery, endoscope minimally invasive surgery, general surgery department surgery, open type wound of orthopaedics departments, plastic and aesthetic surgery, outpatient service and emergency treatment trauma, superficial skin ulcer and the like, and can be applicable to wound fixation, nursing and dressing change of various puncture, conduits and cathetering, and to nursing and dressing change of wound and wound surfaces of individual bruise, contusion, knife wound, small-area burn and the like. The composite chitosan dressing has the effects of hemostasis, heal prompting, analgesia, antibiosis and scar generation prevention.

Description

technical field [0001] The invention belongs to the technical field of hemostatic materials, more specifically, the invention relates to a chitosan composite dressing for promoting wound healing. Background technique [0002] The skin is an important organ of the human body. It plays a role in controlling body temperature, preventing infection, immunity and sensing. Extensive damage to the skin may result from trauma, abrasions, skin ulcers, and burns. Injured skin can easily lead to bacterial infection, loss of body fluids and complications. In the prior art, wound dressings are usually used to protect the wound, absorb exudate, prevent wound infection, maintain a moist environment of the wound and promote wound healing. The wound dressing has the following requirements: 1) It has a softness similar to that of human skin, and it can maintain a certain shape and strength when it is wet; 2) It can maintain a moist environment on the wound surface and has a good ability to a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/28A61L15/44A61F13/02
Inventor 潘大庆许松玲
Owner UNION MEDICAL SUPPLIES
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