Chinese medicine composite for curing climacteric melancholia and application thereof

Abstract

The invention relates to a Chinese medicine composite for curing climacteric melancholia and an application thereof. The Chinese medicine composite is prepared from the following raw materials in parts by weight: 10-20 parts of radix rehmanniae praeparata, 10-20 parts of herba epimedii, 15-25 parts of radix paeoniae alba, 10-20 parts of uncaria, 25-35 parts of fossilia dentis mastodi and 25-35 parts of concha ostreae. The Chinese medicine composite disclosed by the invention accords with the assistant and guide principle of a traditional Chinese medicine on compatibility, and can be used for effectively harmonizing the balanced feedback function among hypothalamus, pituitary and ovarium in the curing process of the climacteric melancholia by being verified through animal and clinical experiments, thereby harmonizing the neuroendocrine network, relieving the anxious emotion, cognitive function, day and night change, mind retardance symptoms, sleep disorder, despairing concept and the like of a patient and effectively regulating and controlling the reproductive endocrine system and the immune system; the Chinese medicine composite disclosed by the invention has the advantages of small toxic side effect, less medicine variety and better curative effect, is suitable for being taken for a long time and is a medicine for safely and effectively curing the climacteric melancholia.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating menopausal depression and its application. Background technique [0002] Menopausal depression mostly occurs in this stage of transition from sexual maturity to old age when women are fertile. According to surveys, the incidence rate of this disease in Europe, America and other countries is 20%, while the incidence rate of menopause depression in Beijing women in my country is 36.1%. And its incidence rate has an increasing trend year by year. [0003] Studies have confirmed that the initiating factors of menopausal depression are due to ovarian function decline, decreased secretion of estradiol, weakened negative feedback to the hypothalamus and pituitary, and increased GnRH, LH, and FSH levels, resulting in HPO dysfunction, which in turn affects Hypothalamic monoamine neurotransmitter imbalance. Psyc...

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Problems solved by technology

However, there is no report about a traditional Chinese medicine composition and its application for the treatment of menopausal depression with few medicinal flavors and significant curative effect.

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