Greening method for preparing aldehydes and ketones through alcohol oxidation of copper catalyst

Abstract

The invention provides a greening method for preparing aldehydes and ketones through the alcohol oxidation of a copper catalyst. The greening method comprises the following steps: taking copper salt as the catalyst, a single-tooth or double-teeth N ligand as the ligand and an organic nitric oxide compound as a co-catalyst, and performing the alcohol aerobic oxidation reaction in water-phase or organic solvent under the existence of alkali and air to prepare an aldehyde and Ketone compound. A copper catalyst system, which is low in cost, easy to obtain, low in toxicity and high in activity, is adopted in the greening method, air is used as an economic, safe and green oxidant, and under the mild condition of the indoor temperature air, the aldehyde and ketone compound is prepared through effective alcohol oxidation. The reaction condition is simple and mild, the operation is easy, the reaction conversion rate is high, the product separation and purification are simple, and the recovery rate is high. The requirement on the reaction condition is relatively low, and the greening method has a good research and industrial application prospect.

Description

technical field [0001] The invention belongs to the field of chemical synthesis, and in particular relates to a green method for preparing aldehyde or ketone compounds through copper catalysis, air as an oxidant, and aerobic oxidation of alcohol. Background technique [0002] Alcohols are a class of organic compounds with a wide range of sources and low prices. However, due to their stable properties, it is difficult to directly participate in organic reactions. They often need to be converted into more active aldehydes, ketones or halogenated hydrocarbons for synthesis. Therefore, many aldehydes and ketones are prepared by oxidation of alcohols. The traditional method of oxidizing alcohols to synthesize aldehydes and ketones usually uses a large number of oxidants, such as oxidants such as chromium oxide, manganese dioxide, and periodic salts, or uses dangerous hydrogen peroxide, etc., so these methods still have many shortcomings, such as metal Oxides are highly toxic, ge...

AI Technical Summary

Problems solved by technology

However, many methods still require the use of noble metal catalysts, highly dangerous pure oxygen as the oxidant, and some methods require the use of highly toxic solvents, so the application potential is limited

So far, there are not many catalytic aerobic alcohol oxidation methods that are inexpensive, low-toxic or non-toxic, efficient, and can be realized under mild conditions with low energy consumption, and some methods require the use of special catalysts, reagents, and additives, which affect the its application

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