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Hypoglycemic traditional Chinese medicine composition and preparation method thereof

A technology of composition and traditional Chinese medicine, which is applied in the field of hypoglycemic traditional Chinese medicine composition and its preparation, and can solve problems such as unsatisfactory effects

Active Publication Date: 2013-12-04
陕西步长高新制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Previously, we applied for an invention patent of a traditional Chinese medicine composition, the publication number of which was CN1857618A, and the publication date was November 8, 2006. However, in the actual application process, we found that the composition and weight ratio of the raw materials of the above Chinese medicine composition The effect of the drug is not ideal enough, so this patent application is to explore through a large number of experiments, and find a more reasonable prescription composition and dosage ratio, and finally use the clinical pharmacodynamics experiment effect as an investigation index to improve the stability of the preparation and biological A traditional Chinese medicine composition for the treatment of diabetes was successfully developed for the purpose of utilization

Method used

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  • Hypoglycemic traditional Chinese medicine composition and preparation method thereof
  • Hypoglycemic traditional Chinese medicine composition and preparation method thereof
  • Hypoglycemic traditional Chinese medicine composition and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0056] Anemarrhena 38.1g, Phellodendron 37.8g, Tianhuafen 20.4g, Rehmannia glutinosa 24.1g, Scrophulariaceae 15.2g, Asparagus 15.2g, Astragalus 20.4g, Digupi 40.1g, Adenophora 15.2g, Dendrobium 22.1g, Polygonatum 20.4 g, Schisandra 15.7g, Codonopsis 12.7g, Ligustrum lucidum 22.1g, Lycium barbarum 13.2g, Chinese yam 20.4g, Gallinarum 33.8g, Pueraria 13.2g, dry at 70°C, grind into coarse powder, add Tween An appropriate amount of -80 is crushed into a powder with an average particle size of less than 75 μm, added with suitable auxiliary materials, mixed evenly, and granulated to make 1000 hard capsules.

Embodiment 2

[0058] Anemarrhena 30g, Phellodendron 50g, Tianhuafen 18g, Rehmannia glutinosa 28g, Scrophulariaceae 12g, Asparagus 20g, Astragalus 40g, Digupi 62g, Adenophora 12g, Dendrobium 16g, Polygonatum 50g, Schisandra 10g, Codonopsis 15g, Ligustrum lucidum 28g, 20g medlar, 18g Chinese yam, 50g gallinaceae, 12g kudzu root, dried at 80°C, crushed into coarse powder, added appropriate amount of Span-80, crushed into a powder with an average particle size of less than 75μm, mixed well, and washed with water Pan pills, dried, made into 1000g pills.

Embodiment 3

[0060] Anemarrhena 62g, Phellodendron 24g, Tianhuafen 40g, Rehmannia glutinosa 16g, Scrophulariaceae 20g, Asparagus 12g, Astragalus 18g, Digupi 30g, Adenophora 20g, Dendrobium 28g, Polygonatum 18g, Schisandra 16g, Codonopsis 10g, Ligustrum lucidum 16g, wolfberry fruit 12g, Chinese yam 40g, gallinaceae 24g, kudzu root 20g, dry at 85°C, grind into coarse powder, add appropriate amount of sodium dodecylsulfonate, grind into powder with average particle size less than 75μm, mix Homogenized, granulated, compressed into tablets, coated, made into 1000 tablets.

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Abstract

The invention relates to a hypoglycemic traditional Chinese medicine composition and a preparation method thereof. The traditional Chinese medicine composition comprises 18 drug substances, namely rhizoma anemarrhenae, cortex phellodendri, trichosanthes root, prepared rehmannia root, figwort root, asparagus, milk vetch, cortex lycii radicis, adenophora stricta, dendrobe, fragrant solomonseal rhizome, shizandra berry, radix codonopsitis, fructus ligustri lucidi, boxthorn fruit, yam, endothelium corneum gigeriae galli and kudzuvine root, and can be made into capsules, tablets, pills and granules with the addition of commonly used auxiliary materials in pharmaceutics; the preparation method of the composition has the characteristics of simplicity, practicability, scientificity and energy conservation.

Description

technical field [0001] The invention relates to a hypoglycemic traditional Chinese medicine composition and a preparation method thereof, belonging to the technical field of pharmaceutical preparations. Background technique [0002] In recent years, with the acceleration of the modernization process and the improvement of people's material living standards, the number of diabetic patients at home and abroad is increasing at an alarming rate year by year. Diabetes has been listed as the third largest disease after cardiovascular and tumors. Diabetes mellitus is a systemic disease mainly caused by the disorder of glucose metabolism caused by the absolute or relative deficiency of insulin in the body. The main cause of the disease is the relative or absolute deficiency of insulin. Emaciation is the main feature, and it has the characteristics of high morbidity, many concurrent syndromes, and cannot be cured. At present, there are more than 40 million diabetic patients in my co...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8984A61K9/20A61K9/16A61P3/10
Inventor 赵步长赵超
Owner 陕西步长高新制药有限公司
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