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Oral liquid mainly comprising radix scrophulariae, radix ophiopogonis, ginseng and manis pentadactyla, preparation method thereof, and detection method of quality standard

A technology of Shenjia oral liquid and detection method, applied in the field of traditional Chinese medicine, can solve problems such as lack of preparation quality control standards, and achieve the effects of strong specificity, accurate results and easy operation

Inactive Publication Date: 2013-11-27
JINAN MILITARY REGION LOGISTICS DEPT MEDICINE & INSTR TEST INST PLA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The preparation is a mixture, the specification is 10mL each, and there is still a lack of quality control standards for this preparation

Method used

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  • Oral liquid mainly comprising radix scrophulariae, radix ophiopogonis, ginseng and manis pentadactyla, preparation method thereof, and detection method of quality standard
  • Oral liquid mainly comprising radix scrophulariae, radix ophiopogonis, ginseng and manis pentadactyla, preparation method thereof, and detection method of quality standard

Examples

Experimental program
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Effect test

Embodiment 1

[0026] The prescription of Xuanmai Shenjia Oral Liquid is: ginseng 200g, Scrophulariae 200g, Ophiopogon japonicus 200g, Shayuanzi 300g, Angelica 150g, Pangolin 100g. The preparation method is: take the above six traditional Chinese medicines and add 3 times the weight of water to decoct three times, boil for 40 minutes each time, filter and combine the three decoctions, concentrate to a relative density of 1.15-1.30 (80°C), add a volume fraction of 95% at room temperature Stir while adding the ethanol aqueous solution, so that the ethanol content is 60%, let it stand for more than 24 hours, recover the ethanol from the supernatant until it has no alcohol smell, add simple syrup, adjust the pH value to 5.0-7.0, add water to 1000mL, stir well Place, filter, fill, and sterilize at 100°C for 30 minutes. Properties: This product is brown liquid, sweet and slightly bitter;

[0027] Get Xuan Mai Shen Jia oral liquid (3 batches altogether, sample 1~3), according to the quality detect...

Embodiment 2

[0040] The prescription of Xuanmai Shenjia Oral Liquid is: ginseng 250g, Scrophulariae 250g, Ophiopogon japonicus 250g, Shayuanzi 250g, Angelica 100g, Pangolin 50g. The preparation method is: take the above six traditional Chinese medicines and add 3 times the weight of water to decoct three times, boil for 40 minutes each time, filter and combine the three decoctions, concentrate to a relative density of 1.15-1.30 (80°C), add a volume fraction of 95% at room temperature Stir while adding the ethanol aqueous solution, so that the ethanol content is 60%, let it stand for more than 24 hours, recover the ethanol from the supernatant until it has no alcohol smell, add simple syrup, adjust the pH value to 5.0-7.0, add water to 1000mL, stir well Place, filter, fill, and sterilize at 100°C for 30 minutes. Properties: This product is brown liquid, sweet and slightly bitter;

[0041] Get Xuanmai Shenjia Oral Liquid (3 batches in total, sample 4~6), according to the quality detection m...

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Abstract

The invention discloses an oral liquid mainly comprising radix scrophulariae, radix ophiopogonis, ginseng and manis pentadactyla, a preparation method thereof, and a detection method of quality standard. Through the utilization of the detection method, the oral liquid mainly comprising radix scrophulariae, radix ophiopogonis, ginseng and manis pentadactyla is enabled to be controllable in quality and stable in curative effect. The oral liquid mainly comprising radix scrophulariae, radix ophiopogonis, ginseng and manis pentadactyla is prepared from the following raw medicines: 150 to 250 g of ginseng, 150 to 250 g of radix scrophulariae, 150 to 250 g of radix ophiopogonis, 250 to 350 g of flatstem milkvetch seed, 100 to 200 g of angelica, and 50 to 150 g of manis pentadactyla. The detection method of the quality standard comprises the steps of utilizing thin-layer chromatography to carry out qualitative identification to radix ophiopogonis and radix scrophulariae, and utilizing an HPLC method to test the content of the ginseng.

Description

technical field [0001] The invention relates to a xuanmai ginseng oral liquid, a preparation method thereof and a quality standard detection method. It belongs to the technical field of traditional Chinese medicine. Background technique [0002] Xuanmai Shenjia Oral Liquid has the effects of nourishing vitality, recovering pulse and strengthening the spleen, nourishing the spleen and lungs, promoting body fluid and nourishing blood, calming the nerves and improving intelligence. It is a non-standard preparation for the medical institution of the Ministry of Health of the Joint Logistics Department of Jinan Military Region. The preparation is composed of six herbs including ginseng, pangolin, shayuanzi, angelica, scrophulariae, and radix japonicus. It is clinically used for tumor patients, leukopenia and gastrointestinal discomfort caused by chemotherapy and radiotherapy, and has a good effect. The preparation is a mixture with a specification of 10mL per bottle. Currently, ...

Claims

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Application Information

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IPC IPC(8): A61K36/8968A61K9/08A61P1/14G01N30/02G01N30/36G01N30/90A61K35/36
Inventor 赵庆华巩伟王爱武刘忠良张振兴文凤娥陈瑶王莉王宝全高媛
Owner JINAN MILITARY REGION LOGISTICS DEPT MEDICINE & INSTR TEST INST PLA
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