Traditional Chinese medicine superfine powder composition resistant to chicken colibacillosis and preparation method thereof

Abstract

The invention discloses traditional Chinese medicine superfine powder composition resistant to chicken colibacillosis and a preparation method thereof. The traditional Chinese medicine superfine powder composition is prepared from dark plum, scutellaria baicalensis, chinese rhubarb, sophora flavescens, folium isatidis, pomegranate bark and liquorice in a certain ratio. The preparation method of the traditional Chinese medicine superfine powder composition comprises the following steps of: selecting the traditional Chinese medicines, and respectively grinding, sieving by adopting a 65-mesh sieve and preparing single Chinese drug common powder; and carrying out superfine grinding on compound traditional Chinese medicine common powder obtained by uniformly mixing single Chinese drug common powder, so that all the compound traditional Chinese medicine common powder can pass through a 400-mesh sieve, subpackaging, and then sealing and storing. The traditional Chinese medicine superfine powder composition preparation prepared by adopting the preparation method has the advantages that pharmaceutical particle size is obviously reduced, cell-wall breaking ratio and release speed of active ingredients are obviously increased, bioavailability of the traditional Chinese medicine superfine powder composition is improved, and pharmacodynamic study results show that a preparation prepared by adopting a superfine grinding process has a more obvious effect when being used for treating chicken colibacillosis compared with a preparation prepared by adopting the traditional process; the traditional Chinese medicine superfine powder composition can be directly used as drinking water, and a method that traditional Chinese medicine powder can be stirred only and can not be drunk is changed.

Description

technical field [0001] The invention relates to a Chinese veterinary drug composition, in particular to a traditional Chinese medicine superfine powder composition for preventing and treating chicken colibacillosis, and also relates to a preparation method and application of the compound superfine powder composition. Background technique [0002] Escherichia coli (Escherichia coli, E coli) is a normal parasite in the intestinal tract. Under certain conditions, certain serotypes of E. coli can cause a series of infections. In chickens, it is manifested as respiratory tract and soft tissue infection, resulting in Septicemia, air sacculitis, perihepatitis, pericarditis, omphalitis, arthritis, encephalitis, etc. have caused serious losses to the poultry industry. E. coli sepsis is the most common type, common in chickens and turkeys. Escherichia coli enters the blood circulation after infectious or non-infectious factors damage the respiratory mucosa. Chicken colibacillosis (C...

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Problems solved by technology

[0005] In order to solve the problems that the above chemical drugs and antibiotics may cause drug residues and drug resistance, traditional Chinese medicine powders are used in a large amount, the cost is high, and the drug effect cannot be fully exerted, the present invention provides a natural, drug-free, and non-toxic side effect A traditional Chinese medicine composition with significant control effect for preventing and treating colibacillosis in chickens, its preparation method and application

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