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Traditional Chinese medicine composition

A technology of composition and traditional Chinese medicine, applied in the field of traditional Chinese medicine composition

Inactive Publication Date: 2013-10-09
石强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, Xeloda, etc., the incidence of chemotherapy-related diarrhea has increased year by year. Treatment can easily lead to dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc., which not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Effective treatment has become an important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Traditional Chinese medicine composition

Examples

Experimental program
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Effect test

Embodiment approach

[0031] (1) Preparation of the concentrated extract of Cortex Phellodendron and Hawthorn decoction

[0032] According to the compatibility ratio of 1:1, take Phellodendron Phellodendron and Hawthorn, soak in distilled water, heat and decoct, filter, add distilled water to the dregs, soak, decoct, and filter in the same way, mix the two filtrates, heat and concentrate, and filter with an ultrafiltration membrane. Drying under reduced pressure, that is.

[0033] (2) Preparation of Phellodendron Phellodendri Ethyl Acetate Extract

[0034] Phellodendron cortex is crushed, soaked in 95% alcohol for 3 times, combined with ethanol extract, brown extract obtained by distillation under reduced pressure, dispersed in water, extracted with water, diethyl ether and ethyl acetate in sequence, part of ethyl acetate is distilled under reduced pressure, and dried to obtain phellodendron acetic acid ethyl ester extract.

[0035] (3) Preparation of total flavonoids from hawthorn

[0036] Take...

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Abstract

The invention relates to a traditional Chinese medicine composition. The traditional Chinese medicine composition comprises a golden cypress and hawthorn decoction concentration extractive, a golden cypress and ethyl acetate extractive and hawthorn general flavone in a proportion of (5-8): (2-5): (3-7). The traditional Chinese medicine composition has a very good curative effect on cancer chemotherapy related diarrhea and meanwhile has a synergistic effect on cancer chemotherapy.

Description

technical field [0001] The present invention relates to a traditional Chinese medicine composition, more specifically to a traditional Chinese medicine composition composed of Phellodendron phellodendron Hawthorn water decoction concentrated extract, Phellodendron phellodendron ethyl acetate extract and hawthorn total flavonoids, a preparation method of the traditional Chinese medicine composition and the traditional Chinese medicine Use of the composition in the preparation of a medicament for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs, whether used alone or in combination, can cause toxic and side effects in patients...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61P35/00A61P1/12
Inventor 石强
Owner 石强
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