Plant cellulose hard empty capsule preparation method

Abstract

The invention provides a plant cellulose hard empty capsule preparation method, and belongs to the technical field of pharmaceutical adjuvants. The plant cellulose is obtained from plant derivatives such as pine trees, purified cotton and the like. Prepared plant cellulose hard empty capsules comprise colorless and transparent hard empty capsules, colored hard empty capsules and light-shielding hard empty capsules. The preparation method comprises steps of: mixing the plant cellulose, a surfactant, a coagulant aid, a coloring agent and water, forming and drying. The plant cellulose hard empty capsule has performance stability, low water content and no interference with human body metabolism, and is green, environment-friendly, safe and suitable for being filled with various contents.

Description

technical field [0001] The invention relates to a preparation method of plant cellulose hard hollow capsules, belonging to the technical field of pharmaceutical excipients. Background technique [0002] The hard hollow capsule shell is the main outer packaging material for filling medicine and health food, and it is taken into the body together with the endocytosis, which reduces the trouble of entrance and increases the curative effect. Traditional gelatin capsules use gelatin hydrolyzed from animal skin and bone as the main raw material. Although gelatin has good properties when preparing hollow capsules, in recent years, with the frequent occurrence of foot-and-mouth disease, mad cow disease, and bird flu, the safety of gelatin has been increasingly questioned, and some quality defects of hard gelatin capsules themselves , can not meet the needs of the market. [0003] At present, the following problems are prone to occur in the production process of plant-based hollow ...

AI Technical Summary

Problems solved by technology

Although gelatin has good properties when preparing hollow capsules, in recent years, with the frequent occurrence of foot-and-mouth disease, mad cow disease, and bird flu, the safety of gelatin has been increasingly questioned, and some quality defects of hard gelatin capsules themselves , can not meet the market demand

[0003] At present, the following problems are prone to occur in the production process of plant-based hollow capsules: if the raw material of the product has low water content (more solids), the raw material will have poor fluidity and poor homogeneity. Inconsistent and low qualified rate of finished products

If the water content of the product raw materials is increased, the fluidity of the raw materials will be improved, the drying and molding process of the product will be longer, and the power consumption will increase. Moreover, due to the loss of water, the uncertainty of product molding will increase, which will also affect the qualified rate of finished products.

The empty capsules prepared by the existing production process have the disadvantages of different wall thicknesses, large differences in water content, low pass rate, and high energy consumption, and the traditional gelatin empty capsules disintegrate and release within 10 minutes in gastric acid, but the capsules The contents in it are irritating to the stomach, or unstable in case of acid, and need to be disintegrated in the intestine to exert curative effect