Preparation method for enteric plant cellulose hard hollow capsules

Abstract

The invention provides a preparation method for hard hollow capsules from enteric plant cellulose derivatives and belongs to the technical field of pharmaceutic adjuvants. Plant cellulose is prepared from plant derivatives such as pine, purified cotton and the like. Colorless and transparent hard hollow capsules, colored hard hollow capsules, shading hard hollow capsules and the like can be prepared though the preparation method. The preparation method comprises steps of mixing of plant cellulose, surfactants, coagulant aids, coloring agents and water, molding, drying, coating and the like. The plant cellulose hard hollow capsules are advantaged by stable performances, low water content, environmental protection and safety. The plant cellulose hard hollow capsules can be filled by all kinds of contents.

Description

technical field [0001] The invention relates to a preparation method of an enteric-coated vegetable cellulose hard hollow capsule, which belongs to the technical field of pharmaceutical auxiliary material processing. Background technique [0002] The hard hollow capsule shell is the main outer packaging material for filling medicine and health food, and it is taken into the body together with the endocytosis, which reduces the trouble of entrance and increases the curative effect. Traditional gelatin capsules use gelatin hydrolyzed from animal skin and bone as the main raw material. Although gelatin has good properties when preparing hollow capsules, the source is limited, and with the frequent occurrence of diseases such as mad cow disease, foot-and-mouth disease, and bird flu, the quality problems of gelatin capsules themselves have caused consumers to question and worry. [0003] At present, the following problems are prone to occur in the production process of plant-bas...

AI Technical Summary

Problems solved by technology

Although gelatin has good properties in the preparation of hollow capsules, the source is limited, and with the frequent occurrence of mad cow disease, foot-and-mouth disease, bird flu and other diseases, the quality problems of gelatin capsules themselves have caused consumers to question and worry

[0003] At present, the following problems are prone to occur in the production process of plant-based hollow capsules: if the raw material of the product has low water content (more solids), the raw material will have poor fluidity and poor homogeneity. Inconsistent and low qualified rate of finished products

If the water content of the product raw materials is increased, the fluidity of the raw materials will be improved, the drying and molding process of the product will be longer, and the power consumption will increase. Moreover, due to the loss of water, the uncertainty of product molding will increase, which will also affect the qualified rate of finished products.

The empty capsules prepared by the existing production process have the disadvantages of different wall thicknesses, large differences in water content, low pass rate, and high energy consumption, and the traditional gelatin empty capsules disintegrate and release within 10 minutes in gastric acid, but the capsules The contents in it are irritating to the stomach, or unstable in case of acid, and need to be disintegrated in the intestine to exert curative effect