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Traditional Chinese medicinal preparation for treating thromboangiitis obliterans, and preparation method thereof

A traditional Chinese medicine preparation and thrombus occlusion technology, applied in the field of pharmacy, can solve the problems of large side effects, inability to completely cure vasculitis, poor anti-inflammatory effect and the like, and achieve the effects of small side effects, high efficiency and exact curative effect.

Inactive Publication Date: 2014-09-17
王京涛
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Western medicine mainly treats vasculitis with anti-inflammatory and analgesic medicines. Western medicine can indeed improve the condition, but the anti-inflammatory effect is poor and side effects are large, so it cannot completely cure vasculitis

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0052] When the dosage form of the Chinese medicine preparation is a tablet, its preparation method may further comprise the steps:

[0053] The first step: mix the various raw materials of the traditional Chinese medicine preparation in proportion, add ethanol with an alcohol concentration of 80% to 90% relative to the mass of the mixture, heat and reflux for 100 to 140 minutes, extract, and filter to obtain the first 1. extract liquid, add the dregs obtained by filtering, then add ethanol with an alcohol concentration of 75% to 85% relative to the mass of dregs, heat and reflux for 80 to 120 minutes, extract, and filter to obtain a second extract. The first extract and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

[0054] Step 2: Put the dry paste obtained in the first step into an ultrafine pulverizer for 3 to 6 hours, pulverize and sieve to obtain an ultrafine powder of 200 to 400 mesh;...

Embodiment 1

[0063] The tablet that embodiment 1 present invention prepares

[0064] Take 90g of Jiazhu, 160g of Guizhi, 320g of small red ginseng, 130g of knotweed, 120g of peach kernel, 180g of medlar, 150g of dried ginger, 140g of hawthorn, 170g of Chinese yam, 120g of coix seed, 140g of Achyranthes bidentata, 160g of psoraleae, 110g of Eupatorium, 150g Cordyceps japonicus, 80g Artemisia argyi, 160g Streptococcus sinensis, 140g Honeysuckle and 150g Selaginella;

[0065] Its preparation method comprises the following steps:

[0066] Step 1: Mix the raw materials of the traditional Chinese medicine preparation in proportion, add ethanol with an alcohol concentration of 85% that is 7 times the mass of the mixture, heat and reflux for 120 minutes, extract, filter to obtain the first extract, and filter the obtained dregs Then add 85% ethanol with an alcohol concentration of 5 times relative to the quality of the dregs, heat and reflux for 90 minutes, extract, filter to obtain the second ex...

Embodiment 2

[0069] The capsule prepared by embodiment 2 the present invention

[0070] Take 100g of Jiazhu, 170g of Guizhi, 280g of small red ginseng, 150g of knotweed, 100g of peach kernel, 160g of medlar, 170g of dried ginger, 150g of hawthorn, 200g of Chinese yam, 100g of coix seed, 120g of Achyranthes bidentata, 190g of psoraleae, 100g of Eupatorium, 140g of Cordyceps japonicus, 90g of Artemisia argyi leaves, 170g of Streptococcus sinensis, 130g of honeysuckle and 140g of Selaginella;

[0071] Its preparation method comprises the following steps:

[0072] The first step is to mix Jiazhu, Guizhi, small red ginseng, Polygonum cuspidatum, peach kernel and Selaginella in proportion, add 6 times the water to extract the volatile oil, and clathrate the obtained volatile oil with β-cyclodextrin, the volatile oil The ratio of β-cyclodextrin to β-cyclodextrin is 1:6, stirred for 130 minutes, and the temperature is 50°C to obtain the clathrate of volatile oil, which is set aside; in addition, ...

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PUM

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Abstract

The invention discloses a traditional Chinese medicinal preparation for treating thromboangiitis obliterans, and a preparation method thereof. The traditional Chinese medicinal preparation comprises Pangolin Scales, cassia twig, Salvia trijuga, Rhizoma Polygoni Cuspidati, Peach Seed, Lycium Chinense, dry ginger, hawthorn fruit, Chinese yam, coix seed, Achyranthes bidentata, Malaytea Scurfpea Fruit, Herba Lycopi, Rabdosia rubescens, Artemisia argyi, rhizome of Whiteback Greenbrier, honeysuckle flower and Herba Selaginellae. The traditional Chinese medicinal preparation utilizes the traditional Chinese medicinal theory in China, has the effects of channel warming, cold expelling, dampness removing, detoxifying, blood circulation promoting, blood stasis removing, and spleen, liver and kidney tonifying, and has the advantages of definite curative effect, fast effectiveness, high effective rate, and small side effects.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a traditional Chinese medicine preparation for treating thromboangiitis obliterans and a preparation method thereof. Background technique [0002] Thromboangiitis obliterans is called vasculitis for short. Refers to a chronic persistent and progressive vascular inflammatory lesion of peripheral vessels (medium and small arteries and veins), leading to thrombosis and occlusion of the vessel lumen. The lesions mainly involve the medium and small arteries of the distal extremities, and the accompanying veins and superficial veins are also often involved, mainly the lower extremities. In severe cases, ulcers and gangrene that are not easy to heal may occur on the extremities, which may lead to permanent dysfunction or loss of limbs, or even death. [0003] Western medicine treatment of vasculitis is mainly based on anti-inflammatory and analgesic western medicines. Western medicin...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9068A61P9/14A61K35/36
Inventor 王京涛柳春华吕咸进全淼王永萍
Owner 王京涛
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