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Traditional Chinese medicinal composition for treating oral lichen planus and application

A technology of oral lichen planus and composition, which is applied in the field of traditional Chinese medicine composition for the treatment of oral lichen planus, can solve the problems of increasing number of patients, easy recurrence, severe clinical symptoms, etc., and achieve the effects of high safety, safe medication and high cure rate

Inactive Publication Date: 2013-09-04
卢恕来
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Because oral lichen planus is often accompanied by blisters, ulceration, and erosion of the oral mucosa, the patient feels obvious spontaneous pain or trigger pain when eating, the clinical symptoms are severe, and the treatment is difficult. Patients with increased mental stress
At the same time, because of its complex etiology, unstable condition, and frequent recurrent attacks, there are currently no particularly effective drugs and methods at home and abroad.

Method used

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  • Traditional Chinese medicinal composition for treating oral lichen planus and application

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Herbal medicine prescription: Codonopsis 120 grams, Xu Changqing 120 grams, Plantago 120 grams, coix seed 250 grams, peach kernel 250 grams, yam 250 grams, black snake 170 grams, white and 170 grams.

[0029] Preparation method: Weigh and combine the above-mentioned medicinal materials, add water to decoct twice, add water for the first time to 10 times the weight of the medicinal materials, decoct for 2 hours, add water for the second time to 8 times the weight of the medicinal materials, and decoct for 1.5 hours , combined decoction, 0.08MPa, concentrated under reduced pressure at 65°C to a relative density of 1.15 at 65°C, added 95% (v / v) ethanol to make the alcohol content reach 85% (v / v), stirred, and stood overnight , filtered, and the filtrate was concentrated under reduced pressure at 0.08MPa and 65°C to a relative density of 1.20 at 65°C, and was prepared into an oral liquid by adding water and sucrose.

Embodiment 2

[0031] Herbal medicine prescription: Codonopsis 120 grams, Xu Changqing 120 grams, Plantago 120 grams, coix seed 250 grams, peach kernel 250 grams, yam 250 grams, black snake 170 grams, white and 170 grams.

[0032] Preparation:

[0033] The first step, prepare clear cream powder:

[0034] 1) Material preparation: Weigh the above-mentioned Chinese medicinal materials cleaned according to the prescription amount, and set aside;

[0035] 2) Decoction: add water to decoct, add water to each pot of the first decoction to be 6 times the total amount of medicinal materials, heat and boil for 4 hours, the extract is filtered through a 200-mesh filter and enter the sedimentation tank; the second decoction adds 6 times the amount of medicinal materials The water is heated and extracted, kept boiling for 4 hours, and the extract is filtered through a 200-mesh filter and enters the sedimentation tank;

[0036] 3) Precipitation: The extract is deposited in the precipitation tank for 30 ...

Embodiment 3

[0042] Embodiment 3 Chinese medicine composition of the present invention is to the treatment observation of oral lichen planus patient

[0043] 47 patients diagnosed with oral lichen planus were treated and observed, including 18 males and 29 females, the oldest was 75 years old, the youngest was 26 years old, and the average was 44.9 years old. Erosion occurred in the cheeks on both sides, mainly in the buccal mucosa of the bilateral posterior teeth. There were 6 cases with erosion area 2cm.

[0044] Exclusion criteria for confirmed patients: suffering from other established oral mucosal diseases; suffering from serious systemic diseases and tumors; using antibiotics within 1 month and immune preparations within 3 months; certain drugs or amalgam Alloy fillings may cause lichen-like reactions; those who have a history of smoking and alcoholism within 3 months; pregnant or breastfeeding women; those who cannot follow the doctor's prescription or have incomplete records of th...

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Abstract

The invention relates to a traditional Chinese medicinal composition for treating oral lichen planus and an application. The composition is prepared from the following traditional Chinese medicinal materials in parts by weight: 8-16 parts of root of pilose asiabell, 8-16 parts of paniculate swallowworf root, 8-16 parts of plantago asiatica, 20-30 parts of coix seed, 20-30 parts of peach seed, 20-30 parts of yam, 12-20 pars of garter snake and 12-20 pars of rhizoma bletillae. The traditional Chinese medicinal composition provided by the invention has an obvious curative effect of treating oral lichen planus and is high in safety.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating oral lichen planus and its application. Background technique [0002] Oral lichen planus is a disorder of mucocutaneous keratosis accompanied by chronic superficial inflammation. Skin and mucosal lesions can occur alone or simultaneously, and are one of the most common diseases in oral mucosal diseases. Modern medicine also has no clear etiology of oral lichen planus. It is believed that it may be related to mental factors, infections, drugs, chronic lesions, systemic diseases, enzyme abnormalities, endocrine abnormalities, or qi stagnation and blood stasis. This disease is prone to occur in middle-aged people, and women are more than men. Because oral lichen planus is often accompanied by blisters, ulceration, and erosion of the oral mucosa, the patient feels obvious spontaneous pain or trigger pain ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61P1/02
Inventor 卢恕来王云龙郑建金
Owner 卢恕来
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