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Traditional Chinese medicine extract

A technology of extracts and natural medicines, applied in drug combinations, antineoplastic drugs, pharmaceutical formulations, etc., to achieve increased inhibitory effects, obvious synergistic effects, and good synergistic effects

Inactive Publication Date: 2013-09-04
张宗升
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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Embodiment approach

[0034] The first step: preparation of various extracts

[0035] (1) Preparation of concentrated extract of Alisma yam decocted in water

[0036] According to the compatibility ratio of 1:1 or 1-4:1, take Alisma and yam, soak in 10 times the amount of distilled water for 1 hour, heat and decoct on an electric stove with asbestos net for 1 hour, filter with silk cloth, save the filtrate, and recycle the drug residue. Add 6 times of distilled water, soak, decoct, and filter in the same way, mix the two filtrates, heat and concentrate to a small volume, filter with an ultrafiltration membrane, and dry under reduced pressure at 70°C for 36 hours in a vacuum drying oven to obtain a brown-yellow powder.

[0037] (2) Preparation of Alisalpine alcohol B acetate

[0038] Alisma coarse powder was percolated with 80% ethanol, and the ethanol was recovered to 10%, and the obtained oily extract was applied to a silica gel column, and after elution with a volume ratio of 10:1 petroleum ethe...

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Abstract

The invention relates to a natural pharmaceutical composition and its preparation method and use in preparation of drugs for reducing toxicity and improving treatment effects in cancer chemotherapy. The natural pharmaceutical composition is composed of rhizoma alismatis-Chinese yam water-decoction condensation extract, alisol B acetate, ethanol extract of Chinese yam and Chinese yam polysaccharide according to a ratio of 3-6: 2-5: 3-5: 4-9. The natural pharmaceutical composition has excellent effects of treating cancer chemotherapy-related diarrhoea and can improve cancer chemotherapy effects.

Description

technical field [0001] The present invention relates to a natural medicine composition, more specifically to a natural medicine composition composed of alisma yam decoction concentrated extract, alisma terpene alcohol B acetate, yam ethanol extract and yam polysaccharide. The preparation method of the natural medicine composition and the use of the natural medicine composition in preparing medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs, whether used alone or in combination, can cause toxic and side effects such as diarrhea in patients. Diarrhea after tumor chemotherapy is also called chemotherapy-associated dia...

Claims

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Application Information

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IPC IPC(8): A61K36/8945A61P1/12A61P35/00A61K31/715A61K31/56
Inventor 张宗升
Owner 张宗升
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