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Improvement for preparation method of Chinese material medical preparation for treating primary hepatic carcinoma

A technology for primary liver cancer and traditional Chinese medicine preparations, which can be used in pharmaceutical formulations, medical raw materials derived from mollusks, medical raw materials from arthropods, etc., and can solve the problems of low yield of volatile oil and volatile components of volatile oil.

Inactive Publication Date: 2013-06-26
KAMP PHARMA
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AI Technical Summary

Problems solved by technology

The application documents with publication numbers CN 1644213 and CN1593523 disclose the traditional preparation process: the yield of volatile oil in the extraction process is not high, and the drying process adopts a low-temperature drying method (spray drying method), and the volatile oil components are volatile

Method used

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  • Improvement for preparation method of Chinese material medical preparation for treating primary hepatic carcinoma
  • Improvement for preparation method of Chinese material medical preparation for treating primary hepatic carcinoma
  • Improvement for preparation method of Chinese material medical preparation for treating primary hepatic carcinoma

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Embodiment Construction

[0006] 1. Determination of the best extraction process

[0007] The steam distillation method is used to extract the volatile oils of 8 medicinal materials such as agarwood, Atractylodes macrocephala, tangerine peel, Patrinia, turmeric, capillary, Cyperus cyperi and Bupleurum. After preliminary test results and literature reports, three factors that have a greater impact on the extraction of volatile oil: soaking time, water addition, and reflux time were investigated and studied, and each factor took three levels. Take 55.5g of agarwood, 554g of Atractylodes macrocephala, 554g of tangerine peel, 554g of Patrinia, 554g of turmeric, 554g of capillary, 554g of Cyperus cyperi, and 277g of Bupleuri according to the proportion of the prescription. Under parallel operating conditions, according to (L 9 (3) 4 ) for the orthogonal test, separate the volatile oil, and dehydrate it with anhydrous sodium sulfate for later use. Taking the total amount of volatile oil as the investigat...

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Abstract

The invention relates to an improvement for a preparation method of a Chinese material medical preparation for treating primary hepatic carcinoma, the Chinese material medical preparation comprises the following raw materials: Codonopsis pilosula, white atractylodes rhizome, ground beeltle, Sculellaria barbata, semen coicis, oyster, rhizoma cyperi, turtle shell, Astragalus mongholicus, rheum officinale, herba patriniae, radix curcumae, oriental wormwood, capillary Artemisia, agilawood, Paris polyphylla, pericarpium citri reticulatae, Poria cocos, Sappan Wood, caulis clematidis armandii, peach kernel and radix bupleuri; agilawood fine powder employs a superfine crushing method on the basis of a traditional preparation method, a drying process employs microwave vacuum drying. The problems of incompletely extraction of effective constituents, low solubility of the agilawood fine powder, storage of traditional Chinese medicine volatile oil, drying of volatile organic constituents, so that the bioavailability of the preparation is increased.

Description

technical field [0001] The invention relates to an improvement of a preparation method of a traditional Chinese medicine compound preparation, in particular to an improvement of a preparation method of a Ganfule preparation. Background technique [0002] Compound Chinese medicine preparation - "Ganfule" is composed of Codonopsis, Atractylodes macrocephala, ground beetle, Scutellaria barbata, coix seed, oyster, Cyperus cyperi, turtle shell, astragalus, rhubarb, Patrinia, turmeric, capillary, agarwood, Composed of Chonglou, Chenpi, Poria, Sappan, Chuanketong, peach kernel and Bupleurum, it has the effects of invigorating the spleen and regulating qi, removing blood stasis and softening hardness, clearing heat and detoxifying, and is suitable for the treatment of primary liver cancer with liver stasis and spleen deficiency as the main syndrome. The application documents with publication numbers CN 1644213 and CN1593523 disclose the traditional preparation process: the yield of ...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/48A61P35/00C11B1/10A61K35/56A61K35/64A61K35/586A61K35/618
Inventor 陈锋张静贺莲
Owner KAMP PHARMA
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