External preparation for spot treatment
A technology for external preparations and stains, applied in skin care preparations, cosmetic preparations, cosmetic preparations, etc., can solve problems such as unsatisfactory effects
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Embodiment 1
[0007] Embodiment 1: This preparation contains the raw material of following weight ratio
[0008] Hydroquinone 3, Arbutin 15, Oleuropein 15.
Embodiment 2
[0009] Embodiment 2: This preparation contains the raw material of following weight ratio
[0010] Hydroquinone 3, Arbutin 20, Oleuropein 10.
Embodiment 3
[0011] Embodiment 3: Freckle-removing effect experiment
[0012] Experimental materials: ointment of this preparation, Chunzhixiu spot-removing cream (Guangzhou Meiyuan Cosmetics Co., Ltd.), and mice provided by Shanghai Slack Experimental Animal Co., Ltd.
[0013] Experimental method: 60 mice were randomly divided into 3 groups: the control group, the externally applied ointment group of this preparation and the commercially available spot-removing cream group. After depilating the abdomen of mice with depilatory agent for 48 hours, take the ointment of this preparation and the commercially available anti-freckle cream 0.3g / 10g, apply the medicine to the abdomen 4 times with an interval of 15 minutes each time, and then inject 0.02mL of histamine solution into the abdomen intradermally, Inject 0.2 mL of 1% Evans blue solution into the tail vein within 2 minutes. After 15 minutes, the animals were sacrificed by cervical dislocation. The abdominal skin was cut open, and the blu...
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