Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

High-strength absorbable magnesium substrate composite orthopedic fixing device and preparation method thereof

An internal fixator, high-strength technology, applied in the direction of internal fixator, fixator, medical science, etc., can solve problems such as difficult to meet mechanical safety requirements

Inactive Publication Date: 2013-02-06
SOUTHEAST UNIV
View PDF6 Cites 19 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The composite material has a wider range of use and better strength and safety than the currently clinically used absorbable polylactic acid orthopedic devices, but it is difficult to meet the mechanical safety requirements for stable fixation in the fixation of large-loaded fractures with higher strength requirements

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] The MB8 magnesium alloy is die-casted and processed into a porous magnesium alloy matrix with a gradient distribution of pores. The outer surface porosity of the porous magnesium alloy matrix is ​​35%-40%, the pore diameter is about 1mm, and the core porosity is 10%. -15%, the pore diameter is about 0.2mm; use 10g / L sodium silicate and 2g / L NaOH as the micro-arc oxidation electrolyte system, immerse the porous magnesium alloy substrate in it, apply 400V voltage, and perform micro-arc oxidation for 10 minutes treatment to make a layer of 10 μm thick magnesia bioceramic bottom layer formed in situ on the surface and the inner hole wall; the porous magnesium alloy matrix accounts for 75% and the polylactic acid with a molecular weight of 900,000 accounts for 25% by weight. The porous magnesium alloy matrix and the polylactic acid polymer material, and the porous magnesium alloy matrix is ​​fixed in the hot-pressing mold; the high-temperature molten polylactic acid polymer m...

Embodiment 2

[0039] The QE22 magnesium alloy is mechanically drilled into a porous magnesium alloy matrix with a gradient distribution of pores. The outer surface porosity of the porous magnesium alloy matrix is ​​30%-35%, the pore diameter is about 1.2mm, and the core porosity is 15%. %-20%, the pore diameter is about 0.3mm; use 10g / L sodium silicate, 3g / L hydroxyapatite nanopowder, 3g / LNaOH as the micro-arc oxidation electrolyte system, and immerse the porous magnesium alloy substrate in it, Apply 400V voltage and carry out micro-arc oxidation treatment for 15 minutes, so that a layer of magnesium oxide and hydroxyapatite composite ceramic bottom layer with a thickness of about 20 μm is formed in situ on the surface and inner hole walls; the porous magnesium alloy matrix accounts for 70% by weight. %, polylactic acid with a molecular weight of 700,000 accounted for 30%, respectively weighed an appropriate amount of porous magnesium alloy matrix and polylactic acid polymer material, and fi...

Embodiment 3

[0041] The AE21 magnesium alloy is die-casted and processed into a porous magnesium alloy matrix with a gradient distribution of pores. The outer surface porosity of the porous magnesium alloy matrix is ​​25%-30%, the pore diameter is about 1mm, and the core porosity is 10%. -15%, the pore diameter is about 0.2mm; use 10g / L sodium silicate, 3g / L hydroxyapatite nanopowder, 3g / LNaOH as the micro-arc oxidation electrolyte system, immerse the porous magnesium alloy substrate in it, and apply 400V voltage, micro-arc oxidation treatment for 15 minutes, so that a layer of magnesium oxide and hydroxyapatite composite ceramic bottom layer with a thickness of about 20 μm is formed in situ on the surface and internal pore walls; the porous magnesium alloy matrix accounts for 65% by weight Polylactic acid with a molecular weight of 500,000 accounts for 35%, and an appropriate amount of porous magnesium alloy matrix and polylactic acid polymer material are weighed respectively, and the poro...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Thicknessaaaaaaaaaa
Apertureaaaaaaaaaa
Apertureaaaaaaaaaa
Login to View More

Abstract

The invention relates to a high-strength absorbable magnesium substrate composite orthopedic fixing device and a preparation method thereof. The fixing device is mainly formed by bonding and solidifying a low-porosity porous magnesium alloy substrate of which a pore structure presents a regular gradient distribution and a lower-content polylactic acid high-polymer material filled in the pore structure of the low-porosity porous magnesium alloy substrate, wherein the pore structure in the porous magnesium alloy substrate presents a gradient distribution that the porosity is gradually reduced from the surface of the magnesium alloy substrate to a core part or from the edge to the center, and the size of a pore is gradually diminished; and according to the calculation in percentage by weight, the polylactic acid of the high-polymer material for filling accounts for 5-49.9 percent of total weight, and the porous magnesium alloy substrate accounts for 50.1-95 percent of total weight. The fixing device is closer to magnesium alloy in strength, has the advantages of controllable in-body adsorption speed, slow-quick degradation, less hydrogen evolution moderate quantity and the like, is particularly suitable for the bone trauma surgery with high strength requirement and big volume, the bone defect repair surgery, the plastic surgery and other absorbable orthopedic fixed implantable devices applied to the clinical.

Description

technical field [0001] The invention relates to a high-strength absorbable magnesium-based composite orthopedic internal fixator, in particular to a low-porosity porous magnesium alloy matrix whose pore structure presents a gradient regular distribution and the lower content of the pore structure filled The polylactic acid polymer material is made by high-temperature bonding and solidification, in which the pore structure in the porous magnesium alloy matrix shows that the porosity gradually decreases from the surface of the magnesium alloy matrix to the core or from the edge to the center, and the pore size gradually decreases. gradient distribution. The invention has the advantages of high strength, controllable absorption rate in the body, slow first and then fast degradation, less hydrogen evolution relaxation, etc., and is especially suitable for clinical applications such as bone trauma surgery, bone defect repair surgery, and plastic surgery with high strength requireme...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61L31/06A61L31/02A61L31/08A61B17/68
Inventor 储成林薛烽郭超白晶盛晓波董寅生林萍华
Owner SOUTHEAST UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com