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Schlemm tube expansion bracket and combined body thereof

A technology of Schlemm's canal and assembly, which is applied in stents, prostheses, medical science, etc., to achieve the effect of reducing serious damage, reducing the incidence rate, and promoting the removal of aqueous humor

Active Publication Date: 2012-12-19
BEIJING TONGREN HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0012] Most of the problems with existing glaucoma treatment devices and treatments are due to the drainage of aqueous humor from the interior of the eye to the surface of the eye

Method used

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  • Schlemm tube expansion bracket and combined body thereof
  • Schlemm tube expansion bracket and combined body thereof
  • Schlemm tube expansion bracket and combined body thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] The two ends of the cylindrical or drum-shaped curve are bent into a smooth and blunt small ring 7 toward the inside of the cylindrical or drum-shaped surface.

[0041] The tooth tips of the fold-back teeth are arc-shaped and bend inwardly towards the cylindrical surface or the drum-shaped surface.

[0042] The metal wire is made of titanium-magnesium alloy or cobalt-chromium alloy, and its cross-sectional shape is circular, semicircular, elliptical, semielliptical or rectangular.

[0043] Embodiment 2;

[0044] see figure 2 and image 3 , the housing of another structure of the present invention is a mesh structure 8, the mesh structure includes a plurality of corrugated ring-shaped support structure units 9, the ring-shaped support structure units are arranged in order left and right, each row of ring-shaped support structures The crests corresponding to the units are close to each other, and the troughs corresponding to the ring-shaped support structure units in ...

Embodiment 2

[0046] Embodiment 3;

[0047] A Schlemm's canal (Schlemm) expansion stent, such as Figure 4 As shown, the expansion stent is a cylindrical hollow shell, and the cylindrical surface is formed by an alloy wire 11 arc bent 360 degrees and then bent back 11-1 arc 360 degrees to form a continuous circular curve Composed of rings 12, this structure has higher strength than the cylindrical surface formed by single-wire circular arc winding; at least one end of the alloy wire is an enlarged end 11-2 with a diameter larger than the diameter of the alloy wire, and this enlarged end can be easily A rope is fixed, and the rope is used to facilitate the removal of the stent; in order to make the stent have the function of delivering medicine and releasing slowly, the surface of the alloy wire is coated with a coating with a thickness of 10 microns to 20 microns, and the coating includes adhesive The bottom layer and the drug layer are used to bond the drug to the alloy wire. Usually, the...

Embodiment 3

[0049] In an embodiment, the distance 11-3 between the alloy beads distributed on the cylindrical surface is 20 microns to 50 microns, preferably 30 microns.

[0050] In an embodiment, the alloy wire is titanium-magnesium alloy wire or cobalt-chromium alloy wire.

[0051] Embodiment 4;

[0052] like Figure 5 and Figure 6 As shown, a Schlemm canal (Schlemm) expansion stent assembly includes a cylindrical hollow shell stent and a stent propulsion body 18, and the cylindrical surface is bent by an alloy wire for 360 degrees Then turn back and bend 360 degrees in a circular arc to form a continuous circular curve circle. At least one end of the alloy wire is an enlarged end with a diameter larger than the diameter of the alloy wire; in this embodiment, the propulsion body of the stent is a cylinder. One end of the body is a conical head 18-1, and the other end of the cylinder is provided with a protruding stop ring 18-2. The diameter of the stop ring is 20 microns greater th...

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Abstract

The invention relates to a Schlemm tube expansion bracket and a combined body of the Schlemm tube expansion bracket. The expansion bracket is a hollow cylindrical shell; the cylindrical surface is formed by a continuous round curve loop bent and folded from an alloy wire; the surface of the alloy wire is coated with a coating of 10-50 microns, and the coating comprises an adhesive bottom layer and a drug layer. The tube expansion bracket disclosed by the invention can reduce the damage to the wall of a Schlemm tube, reduces restenosis and multiplication occurrence rate of a cavity of the Schlemm tube, and has good soft performance. The Schlemm tube expansion bracket disclosed by the invention can effectively and lastingly release the drug on a narrow lesion site, and guarantees local precise drug delivery of a target lesion point while reducing a serious damage on the wall of the Schlemm tube caused by the bracket wall, and therefore, the restenosis occurrence rate of the Schlemm tube can be effectively reduced, thereby achieving the purposes of promoting aqueous humour discharge, reducing intraocular tension and treating glaucoma.

Description

technical field [0001] The invention relates to an ophthalmic stent, in particular to a Schlemm canal (Schlemm) expansion stent for placing in the intraocular Schlemm canal (Schlemm) and a combination thereof. Background technique [0002] Glaucoma is a serious public health disease. More specifically, glaucoma is an optic neuropathy (disease of the optic nerve), which is usually caused by poor drainage of aqueous humor in the eye, resulting in increased intraocular pressure. Increased pressure in the eye damages the optic nerve and narrows the field of vision. When the patient has persistent high eye pressure, it can lead to blindness in the patient. [0003] The eye is a hollow structure that contains a clear fluid called "aqueous humor". Aqueous humor is formed in the posterior chamber of the eye via the ciliary body at a rate of approximately 2.5 microliters per minute. The fluid produced at a fairly constant velocity then passes around the lens and through the pupil...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/88A61F2/84A61F2/90
Inventor 王宁利牟大鹏王怀洲
Owner BEIJING TONGREN HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV
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