Whole-body and only-nose compatible breathing toxicity test equipment

Abstract

The invention provides whole-body and only-nose compatible breathing toxicity test equipment which comprises a main gas flow round tube, a lifting rack and experimental animals, wherein the main gas flow round tube and the lifting rack are arranged on a whole-body cabin and can move up and down; a plurality of branch pipes are arranged along the periphery of the main gas flow round tube; a plurality of branch pipes are respectively and oppositely inserted into rat rack mounting holes; only noses of the experimental animals are exposed out; mixed gas flow flows to the noses of the experimental animals through the corresponding branch pipes to be breathed, carbon dioxide gas which is breathed out overflows from rat rack side flow holes and flows downward to an exhaust port along a side flow cylinder to be exhausted so as to complete the only-nose breathing toxicity test; and when the whole-body breathing toxicity test is carried out, the main gas flow round tube is lifted up, single animal cages are arranged at the bottom of the whole-body cabin, the mixed gas flow is diffused downward in the side flow cylinder from the main gas flow round tube along the branch pipes to carry out whole-body breathe-in toxicity test. The whole-body and only-nose compatible breathing toxicity test equipment has the beneficial effects that one set of equipment has functions of the whole-body breathing toxicity test and the only-nose breathing toxicity test; and the whole-body and only-nose compatible breathing toxicity test equipment is widely applied in the scientific research on the occupational health, the military science, the environmental protection, the respiratory medicine and the like.

Description

technical field [0001] The present invention provides a whole body and nose-only respiratory toxicity test equipment. Background technique [0002] With the development of scientific research on people's respiratory diseases, more and more pathological studies require respiratory toxicity experiments to verify the degree of harmful effects of certain gaseous substances on humans. In the past, independent systemic respiratory toxicity test equipment or only The nasal respiratory toxicity test equipment is completed, and the whole body respiratory toxicity test equipment uses the whole body cabin to put experimental animals into the experiment. There are many drugs, imprecise, the skin of the animal will be infected, and the accuracy of the result will be affected by the poisoning of the animal through licking, etc., but only the nasal respiratory toxicity test equipment uses animal fixing frames to restrain the experimental animals and only expose the nose to align with their...

AI Technical Summary

Problems solved by technology

[0002] With the development of scientific research on people's respiratory diseases, more and more pathological studies require respiratory toxicity experiments to verify the degree of harmful effects of certain gaseous substances on humans. In the past, independent systemic respiratory toxicity test equipment or only The nasal respiratory toxicity test equipment is completed, and the whole body respiratory toxicity test equipment uses the whole body cabin to put experimental animals into the experiment. There are many drugs, imprecise, the skin of the animal will be infected, and the accuracy of the result will be affected by the poisoning of the animal through licking, etc., but only the nasal respiratory toxicity test equipment uses animal fixing frames to restrain the experimental animals and only expose the nose to align with their respective noses. The advantages of the gas distribution branch pipe are that it can control the gas to flow only to the nose of the experimental animal without polluting the skin of the experimental animal, and will not cause experimental interference caused by animal licking, and because the flow cavity is small, it can save experimental drugs and control at the same time The mixed gas concentration and other indicators are more accurate, but the disadvantage is that the experimental animals need to be restrained, so the respiratory toxicity test cannot be carried out for a long time, and the experimental animals cannot move freely, so they cannot be close to the natural living conditions, and there are certain experimental errors. The experimental equipment of the two methods Each has its advantages and disadvantages and cannot be completely substituted for each other. The cost of the two types of equipment is relatively high and the floor area is large, which brings irreconcilable contradictions to the application of scientific research institutions and scientific experiments. In order not to occupy more space and reduce the purchase of two The funds for a set of test equipment can be combined with two different methods and functions through a small and convenient change at any time on a set of equipment, and can complete the whole-body respiratory toxicity test or the nose-only respiratory toxicity test, so It is an urgent need to develop a whole-body and nasal-only respiratory toxicity test equipment to complete the above two respiratory toxicity tests

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