MET inhibitors for enhancing radiotherapy efficacy
A radiotherapy and inhibitor technology, which can be used in gene therapy, medical preparations containing active ingredients, antibody medical ingredients, etc., and can solve problems such as inability to eradicate tumors.
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[0040] Some preferred embodiments of the invention are described in detail here by way of non-limiting examples.
[0041] In the following description numerous specific details are given to provide a thorough understanding of the embodiments. Embodiments may be made with or without these specific details, or with other methods, components, materials, and the like. In other instances, well-known structures, materials, or operations are not shown or described in detail to avoid obscuring the embodiments.
[0042] The headings given here are for convenience only and are not intended to interpret the scope or meaning of the embodiments.
[0043] In addition to damaging intracellular targets, ionizing radiation (mostly by generating reactive oxygen species) also modulates the activity of regulatory molecules that control stress and restorative biological responses.
[0044] In this response, transcriptional upregulation of the MET oncogene appears to be a critical event leading t...
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