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Traditional Chinese medicine composition for treating upper respiratory tract viral infection and preparation method thereof

A virus infection, upper respiratory tract technology, applied in drug combinations, respiratory diseases, antiviral agents, etc.

Inactive Publication Date: 2012-08-22
SHENZHEN QI WANG INVESTMENT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The method of prevention and treatment of influenza virus is to use vaccines to prevent the occurrence of viruses according to the antigen-antibody theory, but because the antigens of the viruses are constantly mutating, the vaccines often lose their effectiveness
For antiviral drugs, based on the variability of the virus and the drug resistance of the drug, the prevention and treatment of the virus is still very serious.

Method used

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  • Traditional Chinese medicine composition for treating upper respiratory tract viral infection and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment approach 1

[0036] Weigh 15 grams of perilla leaves, 10 grams of Platycodon grandiflorum, 10 grams of arctium, 10 grams of Baiqian, 10 grams of Bupleurum, 10 grams of perilla, 10 grams of Nepeta, 10 grams of skullcap, and 10 grams of Morus alba 10 grams of Radix Glycyrrhiza, 105 grams of the above ten herbs, add water to decoct the combined filtrate, concentrate, cool, add ethanol to make the alcohol content 20-80%, reclaim the ethanol, concentrate the supernatant into a thick paste, and set aside. Add 2 times the weight of 95% ethanol to the thick paste, stir well, let it stand at room temperature for 24-48 hours, take the supernatant, wash the precipitate with 65% ethanol for 1-2 times, combine the washing liquid with the supernatant, as If there is an alcohol extract, it is also combined with the supernatant, and after being filtered and clarified, it is put into a decompression concentration tank or an alcohol recovery tower to recover ethanol until the liquid has no alcohol smell. Di...

Embodiment approach 2

[0038] Weigh 15 grams of perilla leaves, 10 grams of Platycodon grandiflorum, 10 grams of arctium, 10 grams of Baiqian, 10 grams of Bupleurum, 10 grams of perilla, 10 grams of Nepeta, 10 grams of skullcap, and 10 grams of Morus alba 10 grams of Radix Glycyrrhiza, 105 grams of the above ten herbs, add water to decoct the combined filtrate, concentrate, cool, add ethanol to make the alcohol content 20-80%, reclaim the ethanol, concentrate the supernatant into a thick paste, and set aside. Add β-cyclodextrin, heat to dissolve, stir, filter, and spray dry. Hot air inlet temperature is 180°C, air outlet temperature is 80°C, spray dry powder, add flavoring agent, mix well, and dry granulate the material at 40°C , whole grains, and divided into bags to obtain the granules for treating upper respiratory tract virus infection of the present invention.

Embodiment approach 3

[0040] Weigh 15 grams of perilla leaves, 10 grams of Platycodon grandiflorum, 10 grams of arctium, 10 grams of Baiqian, 10 grams of Bupleurum, 10 grams of perilla, 10 grams of Nepeta, 10 grams of skullcap, and 10 grams of Morus alba , Radix Glycyrrhizae 10 grams, mulberry leaf 10 grams, above 11 flavor medicines are altogether 115 grams, then make oral liquid by the method described in embodiment 1.

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Abstract

The invention discloses a traditional Chinese medicine composition for treating upper respiratory tract viral infection and a preparation method thereof. The composition comprises the following active pharmaceutical ingredients in parts by weight: 5-25g of perilla leaf, 5-25g of platycodon root, 5-25g of great burdock achene, 5-25g of willowleaf swallowwort rhizome, 5-25g of Chinese thorowax root, 5-25g of perilla fruit, 5-25g of schizonepeta spike, 5-25g of baical skullcap root, 5-25g of white mulberry root-bark and 1-15g of liquoric root. The active pharmaceutical ingredients can be matched with excipients and a flavoring agent to be directly or indirectly prepared into pharmaceutically acceptable capsules, oral liquid, granules, syrup, tablets, effervescent particles, dropping pills, aerosol, spraying agent, gargle, mouthwash and a variety of formulations via conventional process steps. The traditional Chinese medicine composition can be clinically used for treating or preventing the upper respiratory tract viral infection caused by influenza virus, rhino virus, coronavirus, parainfluenza virus, respiratory syncytial virus, adenovirus and the like and further has the advantages of good curative effect and high cure rate.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating upper respiratory tract virus infection and a preparation method thereof. Wherein, the upper respiratory tract virus infection is an upper respiratory tract infection caused by influenza virus, rhinovirus, coronavirus, parainfluenza virus, respiratory syncytial virus, adenovirus and the like. Background technique [0002] Upper respiratory tract infection refers to the general term for acute inflammation from the nasal cavity to the throat, and is the most common infectious disease of the respiratory tract. About 70-80% are caused by viruses, and a few are caused by bacteria (Zhu Guiqing, Respiratory Medicine, People's Medical Publishing House, March 1984). Bacterial infections are often secondary to viral infections. Clinically, it is characterized by symptoms such as fever, chills, headache, nasal co...

Claims

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Application Information

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IPC IPC(8): A61K36/605A61K36/73A61K36/752A61K36/899A61K36/904A61K9/20A61P11/00A61P31/12A61P31/14A61P31/20
Inventor 曲敬来高雪陈生齐继贵
Owner SHENZHEN QI WANG INVESTMENT
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