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Application and preparation method of ambroxol hydrochloride in preparation of information therapeutic drug and novel drug prepared by preparation method

A technology of ambroxol hydrochloride and chemotherapeutic drugs, applied in the field of ambroxol hydrochloride new drugs, can solve pain and dizziness, allergic reactions and gastrointestinal discomfort, anorexia, diarrhea, stomach pain, nausea and vomiting, restriction Treatment effect, can not be used twice and other issues, to achieve the effect of reducing drug treatment costs, overcoming side effects, and increasing use value

Inactive Publication Date: 2012-07-25
北京中卫神农慢性病医学研究院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the prior art, ambroxol hydrochloride is used as a chemotherapeutic drug, and there are defects that cannot be overcome so far. The first is the toxic and side effects on the human body, and its annoying adverse reactions include headache and dizziness, anaphylaxis and gastrointestinal tract Epigastric discomfort, anorexia, diarrhea, stomach pain, nausea and vomiting, etc.; second, the treatment window is small. Due to the existence of toxic and side effects on the human body, the effective dose that can be used is very small, which limits the therapeutic effect. The maximum amount of oral administration is one time 15mg, 30mg a day, exceeding the limit can cause poisoning; third, only chemotherapy drugs are used, and the drugs will be metabolized and decomposed or excreted when they enter the human body, so they cannot be used again

Method used

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  • Application and preparation method of ambroxol hydrochloride in preparation of information therapeutic drug and novel drug prepared by preparation method
  • Application and preparation method of ambroxol hydrochloride in preparation of information therapeutic drug and novel drug prepared by preparation method
  • Application and preparation method of ambroxol hydrochloride in preparation of information therapeutic drug and novel drug prepared by preparation method

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Experimental program
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Embodiment

[0044] Take the ambroxol hydrochloride raw material (1) by the following weight: 150 grams of the ambroxol hydrochloride raw material (1) (content ≥ 98.5%), put the raw material (1) into the filling machine, and use a microporous air-permeable paper bag according to the net weight of 15 per bag. The gram is packed into 10 bags, and the heat-melt sealing is made into the ambroxol hydrochloride medicine information stuffing bag (3). Simultaneously, make magnetic suspension (card) (8) container (4) box 10 in addition. The manufacturing method of the magnetic suspension (card) (8) container (4) box is: use plastic mold injection molding to produce an oblate container (4) box with an inner hollow diameter of 4-8cm and a height of 0.8-1.2cm, and the container (4) box A number of holes (5) with a diameter of 0.1 cm are placed on the outside of the lower part, and a magnetic sheet (7) with a magnetic force of 500-1500 Gauss is placed on the concave surface of the top of the container ...

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Abstract

The invention discloses application of ambroxol hydrochloride in the preparation of an information therapeutic drug, a preparation method of the ambroxol hydrochloride and a novel drug prepared by the preparation method. The information treatment drug is characterized in that the drug does not contact a human body directly in the treatment, any substance ingredient of the drug can not be consumed, only the drug information is utilized for physical treatment, but the chemical treatment effect can be achieved, a treatment window is enlarged by more than 1000 times, and the side effects of the chemical treatment are avoided. After the ambroxol hydrochloride is used as the information treatment drug, the contents of active ingredients are not changed, and the ambroxol hydrochloride can be used as the conventional preparation in the chemical treatment for secondary effective use.

Description

technical field [0001] The invention relates to the field of medicines, in particular to a novel ambroxol hydrochloride drug. Background technique [0002] The compound Ambroxol hydrochloride is trans-4-[(2-amino-3,5-dibromobenzyl) amino]-cycloalthanol hydrochloride, chemical formula C 13 h 18 Br 2 N 2 O.HCL, molecular weight 414.57. Ambroxol hydrochloride is a sugar solution dissolving agent, clinically used for the treatment of thick sputum and difficulty expectoration caused by acute and chronic respiratory diseases. The pharmaceutical preparations of ambroxol hydrochloride include tablets, capsules, oral solutions, injections and the like. Known ambroxol hydrochloride drugs are all used as chemotherapeutic drugs, which allow the compound ambroxol hydrochloride molecules to enter the human body (enter the blood through oral absorption), distribute to various tissues, and produce chemical reactions in the human body by drug molecules pharmacological effects. In the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/137A61K47/02A61P11/00
Inventor 杨孟君杨哲
Owner 北京中卫神农慢性病医学研究院有限公司
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