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Method for separating and purifying triglyceride of medium- and long-chain fatty acids

A technology for the separation and purification of fatty acid triglycerides, applied in chemical instruments and methods, fat production, carboxylic acid ester preparation, etc., can solve the problem of reducing the cost of structural lipid production. Obstacles to research in related fields and other issues, to achieve the effect of short heating time, low energy consumption and cost, and easy operation

Inactive Publication Date: 2012-07-18
HEFEI UNIV OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The separation process of column chromatography is complicated, the pretreatment time is long, at least 6h, and the processing capacity is small, which hinders the research in related fields
Supercritical CO 2 The extraction method requires an operating pressure of about 20MPa to maintain a supercritical state, which is very unfavorable for reducing the production cost of structured lipids and maintaining the characteristics of the separated substance

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment l

[0013] Embodiment 1: the separation and purification method of medium and long chain fatty acid triglycerides, comprises the steps:

[0014] (1) Using rapeseed oil and caprylic acid as raw materials, 1,3-specific lipase as a catalyst, one-step enzymatic acid hydrolysis to obtain a mixture of medium and long-chain fatty acid triglycerides; The ester mixture is subjected to the first-stage molecular distillation, and the specific operating parameters are: the feed rate is 2mL / min, the heating temperature is 90°C, the scraper speed is 250r / min, and the vacuum degree is 0.4-0.6Pa. The acid value of the obtained heavy phase is low. At 56.59mgKOH / g (the acid value is determined according to the method of GB / T 5530-2005 / ISO 660:1996);

[0015] (2) In the molecular distillation apparatus, carry out the second-stage molecular distillation on the heavy phase. The specific operating parameters are: feed rate 1mL / min, heating temperature 155°C, scraper rotation speed 150r / min, vacuum degr...

Embodiment 2

[0024] Embodiment 2: the separation and purification method of medium and long chain fatty acid triglycerides, it comprises the steps:

[0025] (1) Using rapeseed oil and caprylic acid as raw materials, 1,3-specific lipase as a catalyst, one-step enzymatic acid hydrolysis to obtain a mixture of medium and long-chain fatty acid triglycerides; The ester mixture is subjected to the first-stage molecular distillation, and the specific operating parameters are: the feed rate is 2mL / min, the heating temperature is 90°C, the scraper speed is 250r / min, and the vacuum degree is 0.4-0.6Pa. The acid value of the resulting heavy phase is lower than 61.84mgKOH / g (acid value determination method is the same as described in (1) in Example 1);

[0026] (2) In the molecular distillation apparatus, carry out the second-stage molecular distillation on the heavy phase, and the specific operating parameters are: the feed rate is 2mL / min, the heating temperature is 145°C, the scraper speed is 250r / ...

Embodiment 3

[0028] Embodiment 3: the separation and purification method of long-chain fatty acid triglyceride, it comprises the steps:

[0029] (1) Using rapeseed oil and caprylic acid as raw materials, 1,3-specific lipase as a catalyst, one-step enzymatic acid hydrolysis to obtain a mixture of medium and long-chain fatty acid triglycerides; The ester mixture is subjected to the first-stage molecular distillation, and the specific operating parameters are: the feed rate is 2mL / min, the heating temperature is 90°C, the scraper speed is 250r / min, and the vacuum degree is 0.4-0.6Pa. The acid value of gained heavy phase is lower than 51.75mgKOH / g, and acid value determination method is with embodiment 1;

[0030] (2) In the molecular distillation apparatus, carry out the second-stage molecular distillation on the heavy phase. The specific operating parameters are: feed rate 2mL / min, heating temperature 150°C, scraper rotation speed 150r / min, vacuum degree 0.4~ 0.6Pa, the obtained distillate ...

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Abstract

The invention relates to a method for separating and purifying triglyceride of medium- and long-chain fatty acids. Triglyceride mixture of medium- and long-chain fatty acids is obtained from rapeseed oil, soybean oil or rice bran oil and caprylic acid as raw materials by one-step enzymatic acidolysis with 1, 3 specific lipase as catalyst. Further separation and purification steps of the above triglyceride mixture include: (1) performing first-stage molecular distillation on the mixture in molecular distillation device to obtain heavy phase; and (2) performing second-stage molecular distillation on the heavy phase in molecular distillation device to give product, which has purity of triglyceride of medium- and long-chain fatty acids up to 88.31-93.11% and acid value reduced to below 2.10 mgKOH / g. The invention realizes substance separation by difference in average free path of molecular movement of different substances, and has the advantages of low distillation pressure, short heatingtime, low operating temperature, high product quality, and high separation and purification degree.

Description

technical field [0001] The invention relates to a method for separating and purifying medium- and long-chain fatty acid triglycerides, in particular adopting secondary molecular distillation technology to separate and purify medium- and long-chain fatty acid triglycerides with high purity. Background technique [0002] Structured Lipids, also known as reconstituted lipids, refer to lipids obtained by adjusting the content and types of fatty acids on triglycerides. It can bind fatty acids with special nutrition and functions to specific positions, retain some or all of the properties of natural oils, enhance immunity, be easily digested and absorbed, and reduce the risk of cancer, cardiovascular disease, and obesity. Among them, medium and long-chain fatty acid triglycerides (that is, MLM-type structured lipids) are the most ideal kind of structured lipids. [0003] At present, the most studied at home and abroad is the enzymatic synthesis of medium and long-chain fatty acid...

Claims

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Application Information

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IPC IPC(8): C11B3/12C12P7/64C07C69/30C07C67/54
Inventor 潘丽军姜绍通操丽丽寿佳菲
Owner HEFEI UNIV OF TECH
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