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Formula of cough-relieving medicament and preparation method thereof

An antitussive drug and a technology for mass parts, which are applied in the field of formula and preparation of antitussive drugs, can solve the problems of instability, high price, increased economic burden on patients and the like

Inactive Publication Date: 2012-07-18
吴宜谦
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Upper respiratory tract infection, bronchitis, pneumonia, acute laryngitis, etc. can all cause cough. Currently, there are many pharmaceutical preparations with antitussive effect on the market. The second is that long-term medication is likely to bring certain side effects to body functions, especially the respiratory system; for pure Chinese medicine preparations on the market, especially oral preparations, the drug effect is slow and unstable, which is conducive to balanced breathing. However, the system cannot eradicate the cause of coughing. Patients need a drug with good curative effect, obvious and stable cough relief effect, and relatively low price to solve the above problems.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0067] The preferred raw material quality of the present invention is (gram):

[0068] Loquat leaves 65-75 Poppy shells 45-55 Baibu 10-18

[0069] Baiqian 6-10 Morus alba 5-8 Bellflower 5-8

[0070] Menthol 0.1-0.2 Sucrose 500-800 Flavor 1-2

[0071] Citric acid 0.2-0.6

[0072] In addition, sodium benzoate 2-4 dextromethorphan hydrobromide 0.5-0.8

[0073] Promethazine hydrochloride 0.5-1.0

[0074] 75% ethanol solution 2-6 distilled water 1000-1500.

[0075] The preparation method of above-mentioned antitussive preparation, comprises the steps:

[0076] 1) Add distilled water to decoct loquat leaves, poppy husks, Baibu, Baiqian, Morus alba, and Platycodon grandiflora for two times. The amount of distilled water is three-quarters of the total distilled water. Each time decoct for 2 hours, and then combine twice decoction, filtered and concentrated for later use;

[0077] 2) Add sodium benzoate to the above solution, stir well to dissolve it, then add sucrose to mix wel...

Embodiment 2

[0081] The present invention also preferably raw material quality is (gram):

[0082] Loquat leaf 65-69 Poppy shell 50-55 Baibu 15-18

[0083] Baiqian 6-9 Morus alba 6-8 Bellflower 6-8

[0084] Menthol 0.15-0.2 Sucrose 600-800 Flavor 1

[0085] Citric acid 0.5-0.6

[0086] In addition, sodium benzoate 2-3 dextromethorphan hydrobromide 0.7-0.8

[0087] Promethazine hydrochloride 0.9-1.0

[0088] 75% ethanol solution 4-6 distilled water 1200-1500.

[0089] The preparation method is as in Example 1.

Embodiment 3

[0091] The mass of each component is (grams):

[0092] Loquat leaves 65 Poppy shells 50 Baibu 15

[0093] Baiqian 6 Morus alba 8 Bellflower 6

[0094] Menthol 0.15 Sucrose 800 Flavor 1

[0095] Citric acid 0.5

[0096] In addition, sodium benzoate 2 dextromethorphan hydrobromide 0.7

[0097] Promethazine hydrochloride 0.9

[0098] 75% ethanol solution 4 distilled water 1200.

[0099] The preparation method is as in Example 1.

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PUM

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Abstract

The invention discloses a formula of a cough-relieving medicament and a preparation method thereof. The medicament is composition solution prepared by procedures such as decoction, filtering, boiling and mixing of folium eriobotryae, pericarpium papaveris, radix stemonae, cynanchum glaucescens, the root bark of white mulberry, platycodon grandiflorum, menthol crystal, cane sugar, citric acid, essence, sodium benzoate, dextromethorphan hydrobromide, promethazine hydrochloride, 75% of alcoholic solution, distilled water and the like. The cough-relieving medicament can be suitable for curing cough caused by various respiratory incentives. After patients orally take the cough-relieving medicament, no body function allergic reaction occurs. The cough-relieving medicament has no toxic or side effect and can be rapidly absorbed and utilized by bodies. The cure purpose of relieving cough and asthma can be achieved by tonifying kidneys, strengthening spleens and moistening lungs. The cough-relieving medicament is low in cost, and the preparation process is simple, convenient and easy to implement.

Description

technical field [0001] The invention relates to an anti-cough drug, in particular to the formula and preparation method of the anti-cough drug. Background technique [0002] Coughing is a protective respiratory reflex action of the human body. The cough reflex can effectively remove secretions in the respiratory tract or foreign objects entering the airway. But cough also has a negative side. Severe cough can lead to respiratory bleeding. If long-term, frequent, severe cough affects work and rest, and even causes sore throat, hoarseness and respiratory muscle pain, it is a pathological phenomenon. Upper respiratory tract infection, bronchitis, pneumonia, acute laryngitis, etc. can all cause cough. Currently, there are many pharmaceutical preparations with antitussive effect on the market. The second is that long-term medication is likely to bring certain side effects to body functions, especially the respiratory system; for pure Chinese medicine preparations on the market,...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/904A61P11/14A61K31/485A61K31/5415
Inventor 吴宜谦
Owner 吴宜谦
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