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Bauhinia championii acetic ether extract, n-butyl alcohol extract and preparation methods and applications thereof

A technology of ethyl acetate extraction and ethyl acetate extraction is applied in the field of medicine to achieve the effects of clear medicinal effect, stable preparation method and controllable quality

Active Publication Date: 2012-07-18
广州高泰生物科技有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003] Literature HONG Z F, ZHENG H Y, XU W, et al.Stydy on resistinflammation and analgesic effect of Kangmeifu BurnsOintment (KBO)[J].Chin J Tradit Med Sci Technol (China Traditional Chinese Medicine Science and Technology), 2007, 14(4): 261 -262. HONG Z F, ZHENG HY, WANG R G, et al. Study on antibacterial activity of Kangmeifu Burns Ointment (KBO) [J]. Chin J Microecol (Chinese Journal of Microecology), 2007, 19(2): 177- 178.] It is reported that the flavonoids in Astragalus have analgesic and anti-inflammatory effects. This document only mentions that the crude total flavonoids have analgesic and anti-inflammatory effects, and does not involve specific compounds

Method used

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  • Bauhinia championii acetic ether extract, n-butyl alcohol extract and preparation methods and applications thereof
  • Bauhinia championii acetic ether extract, n-butyl alcohol extract and preparation methods and applications thereof
  • Bauhinia championii acetic ether extract, n-butyl alcohol extract and preparation methods and applications thereof

Examples

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Embodiment 1

[0037] Example 1 Separation and purification of the components of the ethyl acetate part and n-butanol part of Astragalus

[0038] 1. Extraction and separation

[0039] Take 1000g of the medicinal material of Astragalus chinensis, add 80% ethanol and heat it under reflux to extract 3 times, each time for 1.5h, filter, combine the ethanol solution, recover the ethanol until it has no alcohol smell, and obtain the alcohol extraction extract. Add 2000ml of water to suspend the extract, add petroleum ether to extract 5 times, 1000ml / time, combine the petroleum ether extract, recycle, and obtain an oily substance; add chloroform to the water layer and extract 5 times, 1000ml / time, combine the chloroform extract, Recover and dry to obtain extract; Add ethyl acetate to extract the water layer 5 times, 1000ml / time, combine ethyl acetate extract, recover, dry to obtain extract; Add n-butanol to extract 5 times, 1000ml Each time, the n-butanol extract was combined, recovered, dried to ...

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Abstract

The invention provides a bauhinia championii acetic ether extract, which comprises not less than 0.05 percent by weight of quercetin glycoside and not less than 0.04 percent by weight of myricetin. The invention further provides a preparation method and an application of the bauhinia championii acetic ether extract. The invention further provides a bauhinia championii n-butyl alcohol extract, which comprises not less than 0.1 percent by weight of beta-sitosterol. The invention further provides a preparation method and an application of the bauhinia championii n-butyl alcohol extract. A bauhinia championii acetic ether part and an n-butyl alcohol part are used for treating rheumatoid arthritis, and have definite medicinal effects and controllable quality; moreover, the preparation methods are stable, and are suitable for mass production; and a novel option is provided for clinical treatment.

Description

technical field [0001] The invention relates to ethyl acetate extract and n-butanol extract of astragalus and its preparation method and application, which belong to the field of medicine. Background technique [0002] Longxuteng is the vine of Bauhinia championii Benth., also known as Jiulongteng and Meihuarugudan. It is mainly distributed in Fujian, Jiangxi, Guangxi, Zhejiang, etc., and has the effect of dispelling rheumatism and promoting blood qi. Modern pharmacological studies have proved that the active ingredients of Astragalus chinensis have the functions of expelling wind and dampness, promoting blood circulation and relieving pain, invigorating spleen and regulating qi, and are used to treat rheumatoid arthritis, waist and leg pain, bruises, stomach pain, and malnutrition in children. According to the prescription of Huang Jingang, a well-known doctor in southern Fujian, Kangmeifu Burn Ointment with Longxuteng as the main ingredient has a good clinical effect on tr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/48A61P19/02A61P29/00
Inventor 徐伟陈立典褚克丹李煌郑海音张玉琴
Owner 广州高泰生物科技有限公司
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