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Artificial hollow micro-nano motor and its preparation method

A micro-nano, hollow technology, applied in the preparation of microspheres, microcapsule preparations, manufacturing of microstructure devices, etc., can solve problems such as poor loadability, and achieve good loading function, process stability, and good repeatability.

Inactive Publication Date: 2014-10-08
HARBIN INST OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The present invention solves the problem of poor loadability of existing solid spherical motors, tubular motors and linear motors, and provides artificial hollow micro-nano motors and preparation methods thereof

Method used

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  • Artificial hollow micro-nano motor and its preparation method
  • Artificial hollow micro-nano motor and its preparation method
  • Artificial hollow micro-nano motor and its preparation method

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specific Embodiment approach 1

[0029] Specific Embodiment 1: In this embodiment, the artificial hollow micro-nano motor is composed of a hollow sac-shaped skeleton formed by 1 to 10 polyelectrolyte bilayers and micro-nano catalyst particles located in the capsule formed by the skeleton. The diameter of the capsule is 300nm-1000μm, and the particle diameter of the nano-catalyst particles is 3nm-60nm.

[0030] The artificial hollow micro-nano motor of this embodiment not only has good transportability, but also has a good load function, and has broad application prospects in the field of biomedicine, especially in drug release control, blood purification and clinical diagnosis.

specific Embodiment approach 2

[0031] Embodiment 2: This embodiment differs from Embodiment 1 in that the micro-nano catalyst particles are platinum particles, gold particles, silver chloride particles or catalase. Others are the same as in the first embodiment.

specific Embodiment approach 3

[0032] Specific embodiment three: the difference between this embodiment and specific embodiment one or two is: the polyelectrolyte double layer is made up of cationic polyelectrolyte and anionic polyelectrolyte, wherein cationic polyelectrolyte is polyallylamine hydrochloride (PAH ), polyethyleneimine (PEI), polydimethyldiallylammonium chloride (PDADMAC), chitosan (CS), polyvinylamine (PVAM) or polylysine (PL); anionic poly The electrolyte is sodium polystyrene sulfonate (PSS), polyacrylic acid (PAA), polyglutamic acid (PGA), sodium alginate (SA), or deoxyribonucleic acid (DNA). Others are the same as in the first or second embodiment.

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Abstract

The invention provides an artificial hollow micro-nano motor and a preparation method thereof, relating to artificial motors and preparation methods thereof and solving the problem that the existing solid spherical motor, tubular motor and linear motor are poor in loading performance. The artificial hollow micro-nano motor is made from a polyelectrolyte double-layer skeleton and a catalyst or is made from a cationic polyelectrolyte skeleton and the catalyst; and the preparation method of the artificial hollow micro-nano motor comprises the following steps of: (1) preparing micro-nano catalyst particles; (2) synthesizing a core substrate; (3) synthesizing an artificial hollow micro-nano motor skeleton; and (4) removing the core substrate by using a template solvent so as to obtain the artificial hollow micro-nano motor. The preparation method has the advantages of simplicity and feasibility, stable process, good repeatability and convenience in mass production, and the prepared artificial hollow micro-nano motor is good in transportability and loading function, has a wide application prospect in a plurality of aspects, such as drug release control, blood purification, clinical diagnosis, and is simple in operation. The artificial hollow micro-nano motor prepared by the preparation method provided by the invention is applicable to the medical field.

Description

technical field [0001] The present invention relates to an artificial motor and a method for preparing the same. Background technique [0002] Micro-nano material science is at the forefront of today's high-tech development, with unique sound, light, electricity, heat, magnetism, and force properties, bringing new opportunities to the biomedical field. Micro-nanomotor is a hot field of nanoscience in recent years. It realizes the motor function at the molecular level, that is, completes the load and directional transport at the micro-nano scale. Molecular motors are the basis for forming and constructing active structures and realizing repair functions at the nanoscale. They can do things that artificial machines cannot achieve: they can directly convert chemical energy into mechanical energy without intermediate forms such as thermal energy. And electrical energy, is the current challenge of nanoscience. In recent years, with the continuous progress of science and technol...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): B01J13/02B81C1/00
Inventor 贺强吴英杰
Owner HARBIN INST OF TECH
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