Liquid vitamin and manufacture method thereof

Abstract

The invention discloses liquid vitamin and a manufacture method thereof. The liquid vitamin is produced by 1.5% to 3.0% of fat soluble vitamin, 2.5% to 5.0% of water soluble vitamin, 0.02% to 0.05 % of fat soluble vitamin antioxidant formed by butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT), gallic acid propyl ester or arbitrary combination of BHA, BHT and gallic acid propyl ester, 0.05% to 0.1% of water soluble vitamin antioxidant composed of mercaptoacetic acid and / or 2-mercaptoethanol, 0.005% to 0.05 % of antioxidant synergist composed of citric acid, ethylene diamine tetraacetic acid (EDTA)-2Na, erythorbic acid or arbitrary combination of citric acid, EDTA-2Na and erythorbic acid, 0.2% to 1% of preservative formed by methylparaben, propylparaben, benzyl alcohol or arbitrary combination of methylparaben, propylparaben and benzyl alcohol, 15% to 30% of emulsifier composed of twain and / or OP-10 and 60.8 % to 80.725% of infusion water. The liquid vitamin is produced in a good manufacturing practice (GMP) ten-thousand-stage clean workshop under the situation that the illumination intensity of the workshop is smaller than 20Lux and temperature of the workshop is controlled between 22 DEG C to 25 DEG C. The fat soluble vitamin antioxidant and the water soluble vitamin antioxidant in the liquid vitamin can uniformly and stably coexist in the same solution and are long in storage time.

Description

technical field [0001] The invention relates to a liquid vitamin and a preparation method thereof. Background technique [0002] Liquid vitamin is a compound preparation rich in fat-soluble vitamins and water-soluble vitamins made through a special emulsification process. It has more advantages than powder multivitamins. Compared with powder vitamins, it is easier to absorb, has higher bioavailability, and is more convenient to use. . With the development of large-scale aquaculture, liquid vitamins are gradually being recognized, accepted and used, becoming an emerging product in the field of vitamins, showing a broad market prospect. [0003] However, vitamin itself is a very unstable substance, which is easily oxidized, reduced and degraded. Air, temperature, light, production time, etc. in the production process directly affect the potency of liquid vitamins, and when fat-soluble vitamins and water-soluble vitamins coexist in the same solution, the oxygen content and me...

AI Technical Summary

Problems solved by technology

[0003] However, vitamin itself is a very unstable substance, which is easily oxidized, reduced and degraded.

Air, temperature, light, production time, etc. in the production process directly affect the potency of liquid vitamins, and when fat-soluble vitamins and water-soluble vitamins coexist in the same solution, the oxygen content and metal ions in the solution will also affect the potency of vitamins. Potency, because the traditional production methods often use colloid mill grinding or high-temperature heating process, and are produced in workshops with high light intensity, using ordinary water, without adding compound stabilizers, and some even do not add emulsifiers, so Fat-soluble vitamins and water-soluble vitamins are not easy to coexist in the same solution uniformly and stably. These are the key factors that make liquid vitamins difficult to store

Therefore, most liquid vitamins now only contain fat-soluble vitamins or water-soluble vitamins, which cannot meet the comprehensive nutrition of fed animals