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Medicine controlled release formulation for relieving livestock fluorosis and preparation method thereof

A technology of fluorosis and sustained-release agents, which is applied in the direction of anti-toxic agents, drug combinations, drug delivery, etc., can solve the problems of short validity period of fluoride preparations and repeated drug administration, so as to increase the way of animal administration and reduce the leakage The effect of leakage and increasing duration of action

Inactive Publication Date: 2012-06-27
INST OF ANIMAL SCI & VETERINARY TIBET ACADEMY OF AGRI & ANIMAL HUSBANDRY SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The technical problem to be solved by the present invention is to provide a drug slow-release agent for relieving livestock fluorosis in order to solve the problems of short validity period, repeated administration and high toxicity of the existing fluoride preparations

Method used

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  • Medicine controlled release formulation for relieving livestock fluorosis and preparation method thereof
  • Medicine controlled release formulation for relieving livestock fluorosis and preparation method thereof
  • Medicine controlled release formulation for relieving livestock fluorosis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] A drug sustained-release agent for relieving livestock fluorosis, characterized in that it includes the following components in weight percentage:

[0034] Acetamide 10%

[0035] Ground calcium carbonate 45%

[0036] Binder 5%

[0037] Filler 30%

[0038] Lubricant 1%

[0039] Humectant 9%.

Embodiment 2

[0041] A drug sustained-release agent for relieving livestock fluorosis, characterized in that it includes the following components in weight percentage:

[0042] Acetamide 35%

[0043] Ground calcium carbonate 10%

[0044] Adhesive 30%

[0045] Filler 15.99%

[0046] Lubricant 0.01%

[0047] Humectant 9%.

Embodiment 3

[0049] A drug sustained-release agent for relieving livestock fluorosis, characterized in that it includes the following components in weight percentage:

[0050] Acetamide 30%

[0051] Ground calcium carbonate 27.5%

[0052] Adhesive 30%

[0053] Filler 2%

[0054] Lubricant 0.5%

[0055] Humectant 10%.

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Abstract

The invention provides a medicine controlled release formulation for relieving livestock fluorosis and a preparation method thereof, wherein the medicine controlled release formulation comprises the following components of: 10-35% of acetamide, 10-45% of coarse whiting, 5-30% of adhesive, 2-30% of filling agent, 0.01-1% of lubricating agent and 7-10% of wetting agent. Through improving the formulation, the livestock drug delivery mode is increased, the stimulation of a medicine to the livestock is reduced, all the medicines can be instantaneously released and also can be delivered in a long-acting way, accordingly, different diseases are treated, the invention also can provide tablets with different concentrations, and so different market requirements can be satisfied.

Description

technical field [0001] The invention relates to a chemical drug for relieving fluorosis of livestock (calves, lambs, foals and other young animals), in particular to a drug slow-release agent for relieving fluorosis of livestock and a preparation method thereof. Background technique [0002] Fluorine is one of the essential trace elements for animals, widely exists in the environment and in animals, and participates in the normal metabolism and functional activities of animals. Long-term excessive intake of fluoride not only causes damage to bones and teeth, but also causes pathological damage to various organs and tissues throughout the body, leading to fluorosis. Epidemiological surveys show that fluorosis has become an endemic disease that seriously endangers the health of humans and animals. Recent studies believe that excessive fluorine entering the body breaks the dynamic balance of oxidation and anti-oxidation processes, increases the content of free radicals in the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/10A61K31/16A61K47/38A61K9/22A61P39/02
Inventor 色珠次仁多吉拉巴次旦曾江勇杨德全姚海潮佘永新夏晨阳鲁志平吴金措姆四郎玉珍刘建枝
Owner INST OF ANIMAL SCI & VETERINARY TIBET ACADEMY OF AGRI & ANIMAL HUSBANDRY SCI
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