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Application of black-bone chicken blood to regulation of immunity

A technology for regulating immunity and black-bone chicken, applied in the direction of application, medical raw materials derived from mammals, medical raw materials derived from birds, etc., can solve the problems of high price and poor quality

Active Publication Date: 2014-06-04
CHARIOT CARNATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the active ingredients in Chinese medicinal materials usually need to be extracted through complicated procedures, which are expensive, and fake and inferior Chinese medicinal materials are all over the market, and the quality is worrying

Method used

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  • Application of black-bone chicken blood to regulation of immunity
  • Application of black-bone chicken blood to regulation of immunity
  • Application of black-bone chicken blood to regulation of immunity

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Example 1: Preparation of Silkie Blood Meal

[0024] (1) Silky chicken blood treatment

[0025] Silky chickens are self-bred and provided by Kaixin Industrial Co., Ltd. for preparing silky chicken blood meal. The blood collection method of the silky fowl blood is to directly collect the carotid blood of the silky fowl after the carotid artery is cut open after an electric shock. Put the collected silky chicken blood directly into the freezer at -20°C for freezing; or place it at room temperature until it coagulates into a blood clot naturally, and then put it in the freezer at -20°C for later use.

[0026] (2) Drying process

[0027] The frozen silky chicken blood is then made into powder by freeze-drying, the freeze-drying conditions are -20°C, the pressure is 0.01 torr, the processing time for the output of 100 kg is set to 72 hours, and the water content is controlled below about 5%; or The powder is made by hot air drying. The hot air inlet temperature is about 120°C or h...

Embodiment 2

[0031] Example 2: Experimental animals and experimental design

[0032] Male BALB / c mice were purchased from Lesco Biotechnology Co., Ltd., and they were domesticated and quarantined for 1 to 2 weeks. They were tested on 8-week-old mice. The number of experimental animals in each group was 10. This strain of experimental animals has a wealth of basic reference data and data, which can be applied to specific immune function evaluation tests.

[0033] The experimental animals were kept in a standard animal room with an indoor temperature of 21-25°C, a humidity of 55-75%, and a lighting time of 12 hours. After the experimental animals are domesticated for 1 to 2 weeks, they are judged by the experimenters to ensure that the experimental animals are in good health, and then they are weighed and grouped into S-types. Five animals were raised in one breeding cage. The individual experimental animals were distinguished by ear numbers. Cage cards were attached to indicate the cage number,...

Embodiment 3

[0043] Example 3: The effect of silky chicken blood meal on body weight and spleen weight

[0044] During the experiment, the clinical observation of the animals in each experimental group and the naked eye lesions after sacrifice had no specific eye lesions, and there was no significant difference in the weight change and spleen weight after sacrifice between the groups (Table 1 and Table 2), showing that the silky chicken blood meal It is not toxic to living organisms.

[0045] Table 1 Weight changes

[0046]

[0047] Week 0: the weight of the mice before administration on the first day of the test

[0048] NC: negative control group

[0049] TAL: Silkie blood meal low dose group

[0050] TAM: Medium-dose group of silky chicken blood meal

[0051] TAH: Silkie blood meal high-dose group

[0052] PC: Double Crane Ganoderma Lucidum Capsules

[0053] Table 2 Spleen weight

[0054] Group

Dose (mg / kg)

Number of animals

Spleen weight (g)

Spleen weight change rate

NC

0

10

0.1539±0.0...

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PUM

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Abstract

The invention relates to application of black-bone chicken blood powder. The black-bone chicken blood powder can be used for regulating nonspecific immunological competence, and is used for promoting production of cytokines, promoting multiplication of immune cells of the spleen and promoting the activity of natural killer cells and macrophages.

Description

Technical field [0001] The invention relates to a use for regulating immune activity. Background technique [0002] Due to the advancement of medical technology and the extension of human life span, "population aging" has been a common problem faced by developed countries in recent years. At present, Taiwan has entered the forest of developed countries, and the phenomenon of aging population and the problems caused by it have gradually emerged. . With the onset of aging, the functions of immune-related organs in the human body, including the bone marrow, thymus, spleen, and lymph nodes that produce lymphocytes, will gradually decline, increasing the risk of disease infection and death. In addition to aging, current studies have also shown that modern people have increased the burden on the immune system due to factors such as nutritional disorders, stress, or pollution. Under environmental stimulation, it is easy to cause abnormal secretion of cytokines and cause chronic inflamm...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K35/14A61K9/14A23L1/29A61P37/02A61P37/04A23L33/00A61K35/57
Inventor 邓学凯魏敏伦曾丽芳刘姿锜
Owner CHARIOT CARNATION
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