Chinese medicinal medicament for treating myelodysplastic syndrome (MDS) by mainly using natural indigo and realgar and preparation method of Chinese medicinal preparation

Abstract

The invention discloses a Chinese medicinal medicament for treating myelodysplastic syndrome (MDS) by mainly using natural indigo and realgar and a preparation method of a Chinese medicinal preparation. The Chinese medicinal medicament consists of the following raw materials in parts by weight: 1-130 parts of natural indigo, 1-130 parts of realgar, 1-130 parts of rehmannia root, 1-130 parts of prepared rhizome of rehmannia, 1-130 parts of Chinese yam, 1-130 parts of dogwood fruit, 1-130 parts of indian buead, 1-130 parts of oriental waterplantain rhizome, 1-130 parts of root-bark of tree peony, 1-130 parts of glossy privet fruit, 1-130 parts of malaytea scurfpea fruit, 1-130 parts of south dodder seed, 1-130 parts of prepared fleece flower root, 1-130 parts of heterophylly falsestarwort root, 1-130 parts of parched white atractylodes rhizome, 1-130 parts of Sichuan hypoglauca yam and 1-130 parts of cassia twig. The preparation method of the Chinese medicinal preparation comprises the following steps of: (1) weighing natural indigo and realgar and preparing powder for oral taking; and (2) weighing other raw materials, putting into a boiling and extracting cooker, adding water till the medicinal materials are submerged, starting up steam for steaming twice, filtering, and combining the filtrate to obtain a decoction for oral taking. During clinical application, the Chinese medicinal medicament can be used for increasing the effective ratio of a patient suffering from MDS and a patient with normal chromosome suffering from MDS.

Description

technical field [0001] The invention relates to a traditional Chinese medicine for treating myelodysplastic syndrome mainly with Qingdai and realgar, and a preparation method of a traditional Chinese medicine preparation. Background technique [0002] In the prior art, myelodysplastic syndrome (MDS for short) is a group of acquired clonal disorders originating from hematopoietic stem / progenitor cells. (clonal hematopoiesis) results in gradual replacement of normal hematopoiesis (polyclonal hematopoiesis). MDS is characterized by ineffective bone marrow hematopoiesis, long-term progressive refractory cytopenias, and a high risk of transformation to acute leukemia. MDS occurs in all age groups, and it is more common in the elderly. According to European and American data, the incidence rate is 6.5 / 100,000, and the incidence rate of those over 70 years old is as high as 20-35 / 100,000. It has exceeded the incidence rate of leukemia and has become a serious threat. Diseases of ...

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Problems solved by technology

[0003] The applicant has carried out a lot of research on the treatment of myelodysplastic syndrome (MDS) with traditional Chinese medicine, and found that Qinghuang Powder plus kidney-tonifying and spleen-invigorating traditional Chinese medicine has a good clinical effect on myelodysplastic syndrome (MDS). For details, see " Chinese Journal of Integrated Traditional Chinese and Western Medicine, March 2008, Volume 28, No. 3, Page 216-218: Clinical observation of Qinghuang powder plus kidney-tonifying and spleen-invigorating traditional Chinese medicine in the treatment of myelodysplastic syndrome; however, the above-mentioned Qinghuang powder plus kidney-tonifying and spleen-tonifying traditional Chinese medicine The traditional Chinese medicine was clinically used in 55 cases of MDS patients, and the proportion of effective patients was as low as 74.5%; especially for the treatment of patients with normal chromosomes, the proportion of effective patients was only 72.7%, and the proportion of ineffective patients was as high as 27.3%

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