Near-infrared fluorescence imaging surgery guide device and application thereof

Abstract

The invention relates to a near-infrared fluorescence imaging surgery guide device and an application thereof. The device comprises a near-infrared laser light source, a light collection optical system, a visual light filter, a near-infrared light filter, a color video camera, a near-infrared video camera and a terminal display. The device can conveniently perform position guide and morphic display functions in the process of a lymph excision or inactivation surgery, and meanwhile can be used for analyzing and evaluating the effect of the lymph excision or inactivation surgery. The device is favorable to improving surgery efficiency and accuracy and accumulating surgery treatment experience.

Description

technical field [0001] The present invention relates to a near-infrared fluorescence imaging clinical operation guiding device and its application. Specifically, the present invention relates to a device for guiding the position of resected or inactivated sites such as lymph nodes and its application. Background technique [0002] Labeling biomolecules with radiotracers and fluorescent dyes has been used successfully in biomedical research for several years, but in the field of actual in vivo clinical medical imaging, the use of fluorescent probes in clinical research has been mostly limited to Examination of in vitro stained tissue sections. Until the late 1980s, some researchers attempted to inject exogenous fluorescent dyes into living organisms as contrast agents to distinguish diseased and normal tissues in tumor detection through non-invasive or endoscopic optical measurement methods. In recent years, great achievements have been made in the use of fluorescent indicat...

AI Technical Summary

Problems solved by technology

[0005] (1) The device can only observe and display the area image of the blood containing the fluorescent contrast agent but cannot display the image of the unexcited part of the blood without the fluorescent contrast agent

In this way, the operator can only see the lymphatic body at the irradiated site but not the whole surgical area including the lymphatic body. If you want to see the overall situation of the entire surgical area, you need to turn off the irradiated laser light source, but in this way Then the position and shape of the desired resection site cannot be seen. For this reason, the operator needs to repeatedly switch between irradiating near-infrared light and turning off near-infrared light. The application is very inconvenient and causes trouble during the operation.

[0006] (2) The device provides a means to directly observe the surgical area and the lymphatic body that has absorbed the fluorescent contrast agent through the monitor, but it cannot quantify the position and shape of the lymphatic body, the size and shape of the lymphatic body in the surgical area before and after resection, etc. Record and analysis, also cannot quantitatively provide the evaluation between resection operation and final treatment effect, which is not conducive to the operation personnel to summarize experience, communicate with each other, and improve the level of treatment

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