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A traditional Chinese medicine composition for external use in treating arthralgia syndrome and its preparation method and detection method

A detection method and composition technology, which is applied in the direction of drug combination, pharmaceutical formula, active ingredients of hydroxyl compounds, etc., can solve the problems of toxicity and slow onset of action

Active Publication Date: 2011-12-28
北京创立科创医药技术开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although there are many kinds of Chinese patent medicine preparations for external use at present, they all treat rheumatic arthralgia mainly, and there are problems of slow onset of action and toxicity

Method used

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  • A traditional Chinese medicine composition for external use in treating arthralgia syndrome and its preparation method and detection method
  • A traditional Chinese medicine composition for external use in treating arthralgia syndrome and its preparation method and detection method
  • A traditional Chinese medicine composition for external use in treating arthralgia syndrome and its preparation method and detection method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0234] Embodiment 1: rubber plaster

[0235] Raw material composition:

[0236]

[0237] The above-mentioned eleven medicines, take the nine herbs of Danshen, Piper longum, Achyranthes bidentata, pepper, Zanthoxylum bungeanum, Ligusticum edulis, Shenjincao, kaempferia, and galangal, and grind them into coarse powder. Rolling method (Appendix 10 of the Chinese Pharmacopoeia version in 2005), with 6 times the amount of 85% ethanol as solvent, after soaking for 24 hours, slowly percolate at a speed of 2ml per kg per minute, collect percolation liquid, and reclaim ethanol under reduced pressure To the clear ointment whose relative density is 1.08~1.12 (measured at 60°C), add camphor and borneol after cooling, mix evenly, and add 4.5~5.0 times by weight of the total amount of clear ointment made of rubber, rosin, zinc oxide, lanolin , petrolatum, gasoline (rubber 16.8%, rosin 13.4%, zinc oxide 16.8%, lanolin 2.1%, vaseline 2.9%, gasoline 48.0%), made into paste, paste, cut into...

Embodiment 2

[0238] Embodiment 2: rubber plaster

[0239] Raw material composition:

[0240]

[0241] The above-mentioned eleven medicines, take the nine herbs of Danshen, Piper longum, Achyranthes bidentata, pepper, Zanthoxylum bungeanum, Ligusticum edulis, Shenjincao, kaempferia, and galangal, and grind them into coarse powder. Rolling method (an appendix 10 of Chinese Pharmacopoeia version in 2005), with 6 times of amount 90% ethanol as solvent, after soaking for 24 hours, slowly percolate at a speed of 1.5ml per kg of coarse powder, collect percolation liquid, reduce Press and reclaim ethanol to the clear ointment that relative density is 1.10 (60 ℃ measure), add camphor, borneol after cooling, mix evenly, add 4.7 times by weight of the total amount of clear ointment additionally by rubber, rosin, zinc oxide, lanolin, Vaseline and gasoline base (rubber 16.8%, rosin 13.4%, zinc oxide 16.8%, lanolin 2.1%, vaseline 2.9%, gasoline 48.0%) are made into paste, paste, cut into sections, c...

Embodiment 3

[0242] Embodiment 3: rubber plaster

[0243] Raw material composition:

[0244]

[0245] The above-mentioned eleven medicines, take the nine herbs of Danshen, Piper longum, Achyranthes bidentata, pepper, Zanthoxylum bungeanum, Ligusticum edulis, Shenjincao, kaempferia, and galangal, and grind them into coarse powder. Rolling method (an appendix 10 of the Chinese Pharmacopoeia version in 2005), with 5 times the amount of 80% ethanol as a solvent, after immersion for 24 hours, slowly percolate at a rate of 3ml per kg per minute, collect the percolation liquid, and reclaim ethanol under reduced pressure To a clear paste with a relative density of 1.11 (measured at 60°C), add camphor and borneol after cooling, mix evenly, and add rubber, rosin, zinc oxide, lanolin, vaseline, gasoline and 4.5 times the weight of the total clear paste. The matrix (rubber 16.8%, rosin 13.4%, zinc oxide 16.8%, lanolin 2.1%, vaseline 2.9%, gasoline 48.0%) is made into a paste, paste, cut into secti...

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PUM

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Abstract

The invention discloses an externally applied Chinese medicinal composition for treating Bi syndrome, and a preparation method and a detection method of the Chinese medicinal composition. The Chinese medicinal composition consists of root of red-rooted salvia, long pepper extract, cyathula officinalis, black pepper, pepper, Chinese ligusticum rhizome, common clubmoss herb, kaempferia galanga, galangal, camphor and borneol. The Chinese medicinal composition has obvious effects of improving arthralgia, joint tenderness, anchylosis, joint swelling and other symptoms of a patient suffering from osteo arthritis, and has a definite curative effect. The invention also provides a detection method for a composition preparation. The detection method is high in specificity, and economic and applicable; and a test is stable and the result can be obtained quickly.

Description

technical field [0001] The invention relates to an external pharmaceutical composition, a preparation method and a detection method thereof, in particular to an external Chinese medicinal composition for treating arthralgia syndrome, a preparation method and a detection method thereof. Background technique [0002] Arthralgia syndrome in traditional Chinese medicine refers to the imbalance of qi and blood in the human body. The muscle surface and meridians are attacked by wind, cold, damp, and heat, and the qi and blood meridians are blocked by pathogenic factors. Unfavorable flexion and extension or joint swelling, stiffness, deformity, muscle atrophy, movement disorder, and severe cases affect the viscera. This kind of disease is a common disease, frequently-occurring disease, and lingering and difficult to heal. It is one of the key research projects in the medical field. This disease is similar to the rheumatism category of modern medical autoimmune disease. [0003] A...

Claims

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Application Information

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IPC IPC(8): A61K36/9062A61K9/06A61K9/70A61P29/00A61P19/02G01N30/90G01N30/02A61K31/045A61K31/125
Inventor 李咏水陈洛怡
Owner 北京创立科创医药技术开发有限公司
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