Preparation technology and production method of a new integrated dosage form of Evodia decoction
A production method and a technology for a new dosage form, which are applied in the field of preparation of an integrated new dosage form of Wuzhuyu Decoction
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Embodiment 1
[0040] Prepare the following raw materials by the aforementioned method:
[0041] Extracts, nanoparticles, microcapsules, nanoparticles.
[0042] The composition of the raw materials used to make the active ingredients is——
[0043] 9 parts of Evodia rutaecarpa, 9 parts of ginseng, 18 parts of ginger, and 4 parts of jujube.
[0044] Its manufacturing process is as follows:
[0045] In the GMP10000 clean room, the extract, nanoparticles, microcapsules, and nanoparticles are mixed according to the ratio of 4:2:2:2, and the standards for hard capsules in the first part of the "Chinese Pharmacopoeia" of the 2010 edition are adopted, and no excipients are added. , preservatives, using a fully automatic capsule filling machine to fill hard capsules to make hard capsules. Then carry out internal and external packaging such as counting, bottling, sealing, pasting labels, coding, and packing. Finally, according to the production batch uniform instant sterilization, and issue a ster...
Embodiment 2
[0047] Prepare the following raw materials by the aforementioned method:
[0048] Water decoction concentrate, nano liposome, nanoemulsion, microemulsion.
[0049] The composition of the raw materials used to make the active ingredients is——
[0050] 9 parts of Evodia rutaecarpa, 9 parts of ginseng, 18 parts of ginger, and 4 parts of jujube.
[0051] Its manufacturing process is as follows:
[0052] In the GMP10000 clean room, the decoction concentrate, nanoliposome, nanoemulsion, and microemulsion were mixed in a ratio of 4:2:2:2, and the standards for some soft capsules in the first part of the "Chinese Pharmacopoeia" of the 2010 edition were used. , without adding auxiliary materials and preservatives, the soft capsules are made into soft capsules by using a fully automatic soft capsule filling machine. Then carry out internal and external packaging such as counting, bottling, sealing, labeling, coding, and packing. Finally, according to the production batch uniform ins...
Embodiment 3
[0054] Prepare the following raw materials by the aforementioned method:
[0055] Extract, nanoparticle, nanoemulsion.
[0056] The composition of the raw materials used to make the active ingredients is——
[0057] 9 parts of Evodia rutaecarpa, 9 parts of ginseng, 18 parts of ginger, and 4 parts of jujube.
[0058] Its manufacturing process is as follows:
[0059] In the GMP10000 clean room, after mixing the extract, nanoparticles, and nanoemulsions in a ratio of 4:3:3, the 2010 edition of the "Chinese Pharmacopoeia" Part I of the film preparation standard is adopted, and the film-forming material is polyvinyl alcohol. film former. Cartoning, sealing, sticking labels, printing codes, packing and other internal and external packaging. Finally, according to the production batch uniform instant sterilization, and issue a sterilization report. The size of each film is 2-40 square centimeters, and each film is applied for 12-72 hours. The application site: neck, chest, back, a...
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