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Physiological regulator for maternal animals, and preparation method thereof

A technology for animal use and regulator, applied in animal feed, animal feed, application, etc., can solve the problems of insignificant control effect, low content of active ingredients, increase of drug-resistant strains, etc., and achieve stable and reliable effect, quick effect, and low The effect of incidence

Active Publication Date: 2011-11-09
BEIJING KEEPYOUNG TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the drugs used to prevent and treat maternal animal diseases are mostly antibiotics, hormones, and chemically synthesized drugs. Although these drugs have achieved a certain degree of control effect, they have also brought about a series of drug-resistant strains, endocrine disorders, and drug residues. intractable problem
Although there are some traditional Chinese medicine preparations used to prevent and treat maternal animal diseases in the domestic market, most of them are simply pulverized Chinese medicinal materials or extract preparations made by simple extraction, which have low active ingredient content and poor control effect. non-obvious defects

Method used

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  • Physiological regulator for maternal animals, and preparation method thereof
  • Physiological regulator for maternal animals, and preparation method thereof
  • Physiological regulator for maternal animals, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] Traditional Chinese medicine: 10 parts of dandelion, 8 parts of licorice, 6 parts of motherwort, 5 parts of angelica

[0034] Preparation:

[0035] (1) Bacillus licheniformis is inoculated into common nutrient broth medium, at 37 ℃, 180rpm shaker culture, produces first-grade seed liquid, when bacterial content reaches 10 7-8 When the CFU / ml is about 5%, the primary seed liquid is inoculated into the secondary seed fermenter equipped with nutrient broth with 5% inoculum to expand the cultivation. The cultivation temperature is 34°C and the rotation speed is 180rpm. 9 When the CFU / ml is about, stop the fermentation and set aside;

[0036] (2) Inoculate Saccharomyces cerevisiae into the wort medium, cultivate it on a shaker at 28°C at 180rpm, and produce a first-grade seed liquid. When the bacterial content reaches 10 7-8 When the CFU / ml is about 5%, the primary seed liquid is inoculated into the secondary seed fermenter equipped with nutrient broth with an inoculum amo...

Embodiment 2

[0040] Traditional Chinese medicine: 5 parts of dandelion, 8 parts of licorice, 10 parts of motherwort, 5 parts of angelica, 5 parts of astragalus, 3 parts of epimedium

[0041] Preparation:

[0042] (1) Bacillus subtilis is inoculated into common nutrient broth culture medium, at 37 ℃, 200rpm shaker culture, produces first-grade seed liquid, when bacterial content reaches 10 7-8 When the CFU / ml is about 3%, the primary seed liquid is inoculated into the secondary seed fermenter with an inoculation amount of 3% to expand the cultivation. The cultivation temperature is 37°C and the rotation speed is 200rpm. When the bacterial content reaches 10 9 When the CFU / ml is about, stop the fermentation and set aside;

[0043] (2) Inoculate Lactobacillus thermophiles and Lactobacillus acidophilus into MRS culture medium respectively, culture on a shaker at 37°C at 200rpm to produce first-grade seed liquid, when the bacterial content reaches 10 7-8 When the CFU / ml is about 4.5%, the pri...

Embodiment 3

[0047] Traditional Chinese medicine: 5 parts of dandelion, 5 parts of licorice, 5 parts of motherwort, 6 parts of angelica, 3 parts of astragalus, 2 parts of epimedium, 3 parts of Eucommia, 1 part of ginger, and 3 parts of bellflower.

[0048] Preparation:

[0049] (1) Bacillus licheniformis is inoculated into common nutrient broth medium, at 37 ℃, 220rpm shaker culture, produces first-grade seed liquid, when the bacterial content reaches 10 7-8 When the CFU / ml is about 4%, inoculate the first-level seed liquid with an inoculation amount of 4% into the second-level seed fermenter to expand the culture. The culture temperature is 33.5°C and the rotation speed is 220rpm. 9 When the CFU / ml is about, stop the fermentation and set aside;

[0050] (2) Inoculate Candida utilis into the wort medium, 28 ℃, 220rpm shaker culture, produce first-grade seed liquid, when the bacterial content reaches 10 7-8 When the CFU / ml is about 5%, inoculate the first-level seed liquid with an inoculu...

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Abstract

The invention discloses a special physiological regulator for maternal animals, and a preparation method thereof, and belongs to the field of feed additive. A technical scheme of the physiological regulator comprises: carrying out crushing and screening for dandelion, leonurus, licorice root and angelica; adding soybean meal and / or wheat bran; adding water to carry out immersing; adjusting pH value of the resulting mixture; carrying out a sterilization; inoculating probiotics to carry out a fermentation after cooling, followed by stoving after completing the fermentation to obtain the physiological regulator. With the prepared physiological regulator for the maternal animals, immunity and disease resistance of the maternal animals are raised, incidence rate of genital system infection is effectively reduced, feed inversion rate is increased, mammogenesis is improved, milk yield is raised, incidence rate of mammitis is reduced, and milk quality is improved. The physiological regulator has characteristics of quick onset, stable and reliable effect, no toxic and side-effect, no pollution, no residue, and no drug resistance generating, and meets requirements of safe feed additive and assurance of foods of animal origin. In addition, the physiological regulator for the maternal animals can be adopted as a veterinary drug through raising using dosage of the physiological regulator, and provides a substantial curative effect for prevention and cure of the mammitis.

Description

technical field [0001] The invention relates to a physiological regulator for maternal animals and a preparation method thereof, belonging to the field of feed additives. Background technique [0002] Due to diseases and other reasons, the reproductive function of female animals in the breeding period often suffers from reproductive disorders, such as late estrus, return to estrus, low conception rate, difficulty in conception, small litter size, and stillbirth. Postpartum also often causes severe economic losses due to the death of cubs and poor growth and development of maternal animals due to lack of milk or less milk. The level of lactation and milk quality of maternal animals has a major impact on the survival rate of cubs, weaning weight and disease resistance. At present, the drugs used to prevent and treat maternal animal diseases are mostly antibiotics, hormones, and chemically synthesized drugs. Although these drugs have achieved a certain degree of control effect...

Claims

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Application Information

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IPC IPC(8): A23K1/18A23K1/14A23K1/16A23K10/12A23K10/30A23K10/37A23K50/10A23K50/30A23K50/75
CPCY02P60/87
Inventor 肖传明刘春辉黄远荣
Owner BEIJING KEEPYOUNG TECH
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