Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Assay kit for diagnosis of hypertensive disorders of pregnancy

A technology for pregnancy-induced hypertension and disease diagnosis, applied in the biological field, can solve the problems of missing low-abundance proteins, low sensitivity, time-consuming, etc., and achieve the effect of unique detection method, high specificity, and large market prospects

Active Publication Date: 2014-04-02
THE FIFTH PEOPLES HOSPITAL OF SHANGHAI FUDAN UNIV
View PDF2 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] At present, the classic two-dimensional electrophoresis (2-DE) has been widely used in the study of urine proteomics, but its shortcomings are gradually recognized, such as low sensitivity, time-consuming, and often miss some low-abundance proteins

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Assay kit for diagnosis of hypertensive disorders of pregnancy
  • Assay kit for diagnosis of hypertensive disorders of pregnancy
  • Assay kit for diagnosis of hypertensive disorders of pregnancy

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] 1. Experimental method

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
correlation coefficientaaaaaaaaaa
Login to View More

Abstract

The invention belongs to the field of biotechnologies and relates to an assay kit for diagnosis of hypertensive disorders of pregnancy. The assay kit comprises specific antibodies respectively aiming at Kertin, Alpha-actinin-4, Afamin, Alpha-2-macroglobulin, ALB, SERPINA1, Vimentin, Tubulin beta-2C chain and / or angiotensinogen protein. The assay kit can detect multiple proteins which are expressed differentially and are in urine samples of patients suffering from hypertensive disorders of pregnancy. Information of the above multiple proteins expressed differentially can be as a basis for the research of pathogenesis of preeclampsia nephropathy proteinuria, and provides a clue for the search of biomarkers utilized for an early diagnosis and a forecast of preeclampsia nephropathy. The assay kit provided by the invention is a non-invasive detecting tool of biomarkers of hypertensive disorders of pregnancy, and can be utilized for diagnosing preeclampsia nephropathy and hypertensive disorders of pregnancy.

Description

technical field [0001] The invention belongs to the field of biotechnology, and relates to a kit for diagnosing pregnancy-induced hypertension. Background technique [0002] Hypertensive disorder of pregnancy is one of the most common syndromes associated with pregnancy, which affects 7-10% of pregnant women, mainly including gestational hypertension and preeclampsia; preeclampsia, also known as preeclampsia, is pregnancy-induced hypertension and The main cause of massive proteinuria, its clinical features are hypertension, edema, massive proteinuria, and renal insufficiency after 20 weeks of pregnancy, and gradually aggravated with the increase of pregnancy, and the condition often improves rapidly after delivery, mostly in postpartum 6 Return to normal within a week, no later than 3 months. In 2001, Williams regarded proteinuria as one of the necessary conditions for the diagnosis of preeclampsia, indicating the prevalence of renal damage. Proteinuria is an objective ind...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): G01N33/68G01N33/577G01N33/566
Inventor 陈桂香顾勇张扬
Owner THE FIFTH PEOPLES HOSPITAL OF SHANGHAI FUDAN UNIV
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com