Anti-acne composition containing epidermal growth factors and tea tree oil and preparation method thereof
A technology of epidermal growth factor and tea tree oil, applied in skin care preparations, medical preparations containing active ingredients, drug combinations, etc. Inhibits the growth of pimples, removes pimples, and promotes splitting
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Embodiment 1
[0035] Mix 0.1 μg human fibroblast growth factor FGF-21, 1 g tea tree oil, 0.1 g metallothionein, 1 g chlorhexidine acetate, 0.5 g Tween 80, 0.5 g Span 20, and heat the mixture to 80 °C until Turn into a transparent liquid, as the oil phase, keep warm for 30 min; dissolve 0.5g β-glucan, 0.5g glycerol, 0.5g Carbomer 940, 1g methyl salicylate in deionized water, heat to 40°C, As the water phase; quickly add the oil phase to the water phase, stir at a speed of 1000rmp for 30min for homogenization; then add 0.5g of triethanolamine to adjust the pH of the emulsion to 7, add deionized water until the total volume of the emulsion is 100ml , to prepare an anti-acne composition containing epidermal growth factor and tea tree oil.
Embodiment 2
[0037] Mix 100 μg human fibroblast growth factor FGF-21, 5 g tea tree oil, 0.1 g metallothionein, 1 g chlorhexidine acetate, 1.5 g Tween 80, 0.5 g Span 20, and heat the mixture to 90 °C until 1g pyrrolidone carboxylic acid, 2g xylitol, 1g polyvinyl alcohol, 2g hyaluronic acid, 4g fruit acid and 1g phytosphingosine were dissolved in deionized water and heated to 70°C, as the water phase; quickly add the oil phase to the water phase, and stir at a speed of 3500rmp for 10 minutes to homogenize; then add 0.5g triethanolamine to adjust the pH of the emulsion to 7, add deionized water to the total emulsion The volume is 100ml, and the anti-acne composition containing epidermal growth factor and tea tree oil is prepared.
Embodiment 3
[0039] Mix 50 μg of human fibroblast growth factor FGF-21, 10 g of tea tree oil, 3 g of metallothionein, 0.1 g of chlorhexidine acetate, and 2 g of betaphylline, and heat the mixture to 80 ° C until it becomes a transparent liquid, as the oil phase, Insulate for 20 min; dissolve 1g β-glucan, 1g cellulose acetate, 2g acetate-butyrate fiber, 2g fruit acid, 2g salicylic acid in deionized water, heat to 70°C as the water phase; Quickly add to the water phase, stir at a speed of 2700rmp for 24min to homogenize; then add 2g of ethylenediaminetetraacetic acid to adjust the pH of the emulsion to 7, add deionized water until the total volume of the emulsion is 100ml, and obtain a Anti-acne composition of growth factors and tea tree oil.
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