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Novel eyesight protective agent lutein ophthalmic preparation

An ophthalmic preparation, lutein technology, applied in the direction of medical preparations containing active ingredients, tripeptide ingredients, inorganic active ingredients, etc., to achieve the effects of improving bioavailability, overcoming easy oxidation, and remarkable therapeutic effect

Inactive Publication Date: 2011-09-14
崔晓廷
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Checked scientific and technological literature, patent literature and national food and drug approval literature, but found no identical or similar reports

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Water-soluble lutein 1g, taurine 15g, selenized carrageenan 10mg, zinc glycinate 2g, water-soluble vitamin A 0.15g, glutathione 0.3g, methylparaben 0.2g, menthol 0.1g.

[0024] Precisely weigh each component in the prescription, take water-soluble lutein, taurine, selenium, zinc glycinate, water-soluble vitamin A, glutathione and add appropriate amount of pure water to dissolve; Heat the purified water to dissolve, take the menthol and add purified water to dissolve it and add it to the above solution, then add sodium hyaluronate, glycerin and sodium chloride and stir thoroughly. Adjust the pH value to 7.0-7.4, and add pure water to the total amount. Filter, fill, sterilize, and get ready.

Embodiment 2

[0026] Water-soluble lutein 1.3g, taurine 10g, selenized carrageenan 7mg, zinc glycinate 2.6g, water-soluble vitamin A 0.13g, glutathione 0.2g, glycerin 10g, methylparaben 0.2g, peppermint Brain 0.1g.

[0027] Precisely weigh each component in the prescription, take water-soluble lutein, taurine, selenium, zinc glycinate, water-soluble vitamin A, glutathione and add appropriate amount of pure water to dissolve; Heat the purified water to dissolve, take the menthol and add purified water to dissolve it and add it to the above solution, then add sodium hyaluronate, glycerin and sodium chloride and stir thoroughly. Adjust the pH value to 7.0-7.4, and add pure water to the total amount. Filter, fill, sterilize, and get ready.

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Abstract

The invention discloses a lutein ophthalmic preparation for protecting eyesight, which is prepared from the following raw materials: 5 to 13 parts of water-soluble lutein (based on C4oH56O2), 50 to 80 parts of taurine, 0.1 to 0.5 parts of selenium (based on Se), 10 to 25 parts of zinc (based on Zn), 0.5 to 1.0 part of water-soluble vitamin A, and 0.8 to 2.0 parts of glutathione; an auxiliary material consists of a diluent, a wetting agent, an isoosmotic adjusting agent, a preservative, an antioxygen and water for injection; formulations comprise eye drops, eye lotion and the like; and the lutein ophthalmic preparation is suitable for eye diseases such as myopia, long sight, cataract, glaucoma, retinal pigment degeneration, macular degeneration and the like. Various nutritious factors are reasonably compatible, a blank of a lutein external preparation is filled, and the bioavailability and health-care effect are obviously improved; and through actual application by 300,000 people, the total effective rate for the myopia, cataract and diabetic eye disease is over 90 percent and the lutein ophthalmic preparation has positive promotion valve.

Description

technical field [0001] The invention relates to a lutein ophthalmic preparation and a preparation method thereof, belonging to the technical field of medicines and preparation thereof. Background technique [0002] At present, the incidence of eye diseases is on the rise, which is quite harmful to the human body. In recent years, studies have found that lutein is the only carotenoid that exists in the macula and lens of the human retina. It is selectively deposited in the macular area and in various tissues such as the retina, lens, cornea, choroid, ciliary body, iris, and sclera. It is the most important nutrient component in the human retina and an important component of retinal tissue. Lutein has strong anti-oxidation, anti-light damage ability, and nutritional effect on visual cells. It can prevent oxygen free radicals and harmful light from damaging retinal cells and pigment epithelium, improve the activity of visual cells, and is a key protective substance for the ey...

Claims

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Application Information

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IPC IPC(8): A61K38/06A61K47/36A61P27/02A61P27/06A61P27/10A61P27/12A61K31/047A61K31/07A61K31/185A61K31/198A61K33/04A61K33/30
Inventor 王悦
Owner 崔晓廷
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