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Preparation and quality detection methods of Xianglian disinfectant

A technology of disinfectant and mass fraction, applied in botany equipment and methods, disinfectants, medical preparations containing active ingredients, etc., can solve problems such as toxic side effects, environmental pollution, etc., and achieve stable quality, low cost, and disinfection effect significant effect

Active Publication Date: 2011-09-14
BEIJING CENT BIOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to solve the shortcomings of existing disinfection products such as toxic and side effects and pollute the environment, and to design a Xianglian disinfectant with natural Chinese herbal medicine as the main raw material. The killing and inhibiting effect of the method, and its specific preparation and quality detection methods are given

Method used

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  • Preparation and quality detection methods of Xianglian disinfectant
  • Preparation and quality detection methods of Xianglian disinfectant
  • Preparation and quality detection methods of Xianglian disinfectant

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1: the preparation of Xianglian disinfectant of the present invention

[0035] Weigh 50g of Coptis chinensis, 30g of Sophora flavescens, and 20g of Xu Changqing, mix them evenly and put them into a traditional Chinese medicine extraction tank, add 900ml of water to the tank, heat and boil for 1.5 hours, release the extract in the storage tank, then add 720ml of water, heat Boil for 1.0 hour, release the extract, combine the secondary extracts, filter, concentrate the filtrate under reduced pressure to a relative density of 1.20 (measured at 80°C), and slowly add ethanol when it is cooled to 40°C, so that the alcohol content reaches 60% , fully stirred, after standing for 12 hours, take the supernatant for later use; then take 80g of fenugreek and 30g of Artemisia argyi leaves, mix them evenly, put them into a Chinese medicine extraction tank, add 720ml of water to the tank, heat and boil for 3.0 hours, collect volatile oil, Mix the collected volatile oil with...

Embodiment 2

[0039] Embodiment 2: research on the quality standard of Xianglian disinfectant of the present invention

[0040] The Xianglian disinfectant of the present invention is among dozens of traditional Chinese medicines with antibacterial or bactericidal effects, using modern scientific prescriptions and screening methods to provide technology, to obtain Xianglian which has inhibitory or killing effects on various pathogenic microorganisms disinfectant. It is mainly composed of coptis, flavescens, Xu Changqing, fennel, mugwort leaves, cloves, mint, etc. In order to effectively control the quality and effectiveness of Xianglian disinfectant in actual production, the quality standard of Xianglian disinfectant is specially formulated .

[0041] 1 Instruments and reagents

[0042] 1.1 Instrument

[0043] American Waters-1525 high performance liquid chromatograph; 2487-DAD ultraviolet detector; Breeze chromatographic workstation; chromatographic column: ZORBAX SB-C18 column (4.6×250m...

Embodiment 3

[0075] Embodiment 3: the stability investigation of Xianglian disinfectant of the present invention

[0076] Objective: Taking the properties, pH value, content and bactericidal efficacy of Xianglian disinfectant as detection indicators, the stability of Xianglian disinfectant of the present invention was investigated to provide a scientific basis for clinical use.

[0077] 1 Instruments and Medicines

[0078] 1.1 Instrument

[0079] American Waters-1525 high-performance liquid chromatograph; 2487-DAD ultraviolet detector; chromatographic column: ZORBAX SB-C18 column (4.6 × 250mm, 5μm); Lei Magnetic PHS-25 digital display pH meter (Shanghai Precision Scientific Instrument Co., Ltd. company), constant temperature incubator.

[0080] 1.2 Reagents

[0081] Berberine hydrochloride reference substance (Chinese Institute for the Control of Pharmaceutical and Biological Products); Potassium dihydrogen phosphate (analytical pure); Phosphoric acid (analytical pure); Acetonitrile (ch...

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Abstract

The invention relates to a Xianglian disinfectant, an oral preparation, an injection preparation and a spraying preparation containing a Xianglian composition as well as preparation and quality detection methods thereof. The Xianglian disinfectant comprises the following components: coptis root, clove, sophorae flavescentis, mentha haplocalyx briq, paniculate swallowwort root, Chinese mosla herb,cymbopogon citrates and folium artemisiae argyi. According to the invention, the defects of side and toxic effects, environment pollution and the like in the prior art are overcome. The invention hasthe advantages of simple and convenient preparation process, advanced detection means, stable product quality, excellent killing and inhibiting effects to bacteria, fungi and viruses, environment friendliness, no toxic and side effects and remarkable disinfecting effect.

Description

(1) Technical field [0001] The invention relates to a citronella disinfectant, a preparation for oral administration, injection and spraying containing a citronella composition, a preparation method and a quality detection method thereof. (2) Background technology [0002] Disinfection is the process of killing pathogenic microorganisms in the protected organism and its surrounding environment. It plays a vital role in eliminating the source of infection, cutting off the transmission route, and controlling the occurrence and spread of infectious diseases. Chemical disinfectants are widely used in the production process of animal husbandry, and these preparations are effective if selected properly. But each has its own shortcomings, such as some disinfectants are toxic, irritating, metal corrosive, and environmentally destructive; many disinfectants affect the health of animals to varying degrees, and are not suitable for disinfection with animals; the operating system must h...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P31/00A61P31/04A61P31/10A61P31/12A01N65/44A01N65/32A01N65/28A01N65/22A01N65/20A01N65/12A01N65/08A01P3/00A01P1/00G01N30/90G01N30/02
Inventor 江厚生王秀敏陆凤琪侯晓礁
Owner BEIJING CENT BIOLOGY CO LTD
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