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Preparation method of mulberry particles

A technology of mulberry and granules, which is applied in the field of preparation of mulberry granules, can solve the problems of reducing drug efficacy, increasing production costs, and inability to fully dissolve the active ingredients of mulberry, and achieve the effects of energy saving, convenient cleaning, and shortened production time

Active Publication Date: 2011-08-03
JIANGSU SUNAN PHARMA IND CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Yin deficiency and blood dryness can easily cause weakness of the waist and knees, dizziness, insomnia, dizziness and tinnitus, intestinal dryness and constipation, dry mouth and tongue, premature graying of beard and hair, etc. The main treatment for these diseases is to take medicines that nourish yin and kidney, nourish blood and moisten dryness At present, the more common therapeutic drug is mulberry granule, but the existing preparation method of mulberry granule cannot fully dissolve the active ingredients in mulberry fruit, thereby reducing the drug effect. Therefore, a large amount of mulberry fruit needs to be invested in order to meet the requirements, so that Greatly increased production costs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0014] Embodiment 1: first 1000g mulberry is soaked in water for 2 hours, then decocted twice, each 2 hours, add 10 times the amount of water for the first time, add 8 times the amount of water for the second time, merge the decoction and filter; When concentrated to 60 DEG C, the mulberry extract with a relative density of 1.36 to 1.38 is collected in a 300,000-level clean area; in a 300,000-level clean area, 1250 parts by weight of sucrose are crushed into powdered sugar and passed through a 120-mesh sieve Place in a tank mixer, then add mulberry extract, and mix for 15 minutes to obtain a soft material; granulate the above soft material, and use a YK160 oscillating granulator for granulation. Turn on the power, start the machine for trial operation, stop the machine after there is no abnormality, install the 18-mesh screen, place the receiving tray and start the machine, put an appropriate amount of soft material into the hopper, and rotate and extrude the machine to form pa...

Embodiment 2

[0015] Embodiment 2: first 1000g mulberry is soaked in water for 2.5 hours, then decocted twice, each 2 hours, add 8 times the amount of water for the first time, add 6 times the amount of water for the second time, merge the decoction and filter; merge The decoction is filtered; the filtrate first enters the double-effect concentrator for concentration to a relative density of 1.1 to 1.2 at 60°C, and then moves the concentrate to a vacuum concentration tank for concentration at 60°C with a relative density of 1.36 to 1.36. The mulberry extractum of 1.38 is collected in a 300,000-level clean area; in a 300,000-level clean area, the sucrose of 1250 parts by weight is broken into powdered sugar, placed in a tank mixer after passing through a 120 mesh sieve, and then added mulberry Extraction, mixed for 15 minutes to obtain a soft material; granulate the above soft material, and use a YK160 oscillating granulator for granulation. Turn on the power, start the machine for trial ope...

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PUM

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Abstract

The invention discloses a preparation method of mulberry particles. The method comprises the following steps of: firstly, extracting the active ingredients of mulberries to obtain a mulberry extract; crushing sucrose in a clean area of 300 thousand level into sucrose powder and mixing the sucrose with the mulberry extract to obtain a soft matter; pelletizing the soft matter, and then drying the prepared wet particles with a negative-pressure boiling drying bed at the temperature between 45 DEG C and 65 DEG C; and stopping drying when moisture is not more than 2.0 percent to obtain mulberry particles. The invention has the advantages that warm soaking is carried out before the first decocting, and the speed for dissolving active ingredients of the decocting mulberries out can be accelerated by means of the water dosage adapted for each decocting so as to improve the proportion of the active ingredients in the mulberry particles. In the invention, the production time can be shortened by adopting a double-effect concentrator for concentration, and the preparation method is pollution-free, has dense medicament smell, convenience in cleaning and energy saving.

Description

technical field [0001] The invention relates to a preparation method of a traditional Chinese medicine preparation, in particular to a preparation method of mulberry granules for nourishing yin and kidney, nourishing blood and moistening dryness. Background technique [0002] Yin deficiency and blood dryness can easily cause weakness of the waist and knees, dizziness, insomnia, dizziness and tinnitus, intestinal dryness and constipation, dry mouth and tongue, premature graying of beard and hair, etc. The main treatment for these diseases is to take medicines that nourish yin and kidney, nourish blood and moisten dryness At present, the more common therapeutic drug is mulberry granule, but the existing preparation method of mulberry granule cannot fully dissolve the active ingredients in mulberry fruit, thereby reducing the drug effect. Therefore, a large amount of mulberry fruit needs to be invested in order to meet the requirements, so that Greatly increased production cost...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/605A61P1/14A61P7/06A61K131/00
Inventor 丁子君汤太平胡世成
Owner JIANGSU SUNAN PHARMA IND CO LTD
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