Chinese medicine composition with function of immunological enhancement and application thereof

An immune-enhancing and composition technology, applied in the field of traditional Chinese medicine compositions with immune-enhancing effect, can solve the problems of repeated green barriers to export trade, outbreaks of low antibody titers, immune failures, etc., to improve cellular immunity and humoral immunity, No toxic side effects, small dosage effect

Inactive Publication Date: 2011-07-27
南京日升昌生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to immunization failure and low antibody titers, outbreaks of epidemics occur from time to time
The use of large doses of chemical drugs for treatment has caused drug residues and serious environmental pollution, making export trade repeatedly encountered green barriers

Method used

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  • Chinese medicine composition with function of immunological enhancement and application thereof
  • Chinese medicine composition with function of immunological enhancement and application thereof
  • Chinese medicine composition with function of immunological enhancement and application thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0040] 2 Preparation of Guiqi Drink

[0041] The prescription medicinal materials per 1000ml liquid medicine are: astragalus 300g, angelica 200g, epimedium 200g, medlar 100g, atractylodes 100g, hawthorn 100g.

[0042] For the above six flavors, add 10 times the amount of water to decoct 3 times (considering the water absorption rate of the medicinal materials, add 2 times the amount of water for the first time), each time for 1.0h, filter, centrifuge at 16000r / min for 15min, mix the supernatant, and concentrate When the crude drug content is 1g / ml, add sodium benzoate in an amount of 1g / L, stir evenly, and aseptically fill.

[0043] 3 Pharmacological study on the efficacy of Guiqi Decoction

[0044] 3.1 Effect of Guiqi Decoction on serum antibody titer of Newcastle disease vaccine immunized chicks

[0045] Guiqi decoction is set to 6 doses of 0.25g / feather, 0.5g / feather, 0.75g / feather, 1.0g / feather, 1.25g / feather, 1.5g / feather, and the chicks are immunized with Newcastle dis...

Embodiment 1

[0062] The preparation of embodiment 1 oral liquid

[0063] The prescription medicinal materials per 1000ml liquid medicine are: astragalus 300g, angelica 200g, epimedium 200g, medlar 100g, atractylodes 100g, hawthorn 100g.

[0064] Add the above six herbal medicines with 10 times the weight of Chinese herbal medicines (in consideration of the water absorption rate of the medicinal materials, add 2 times more water for the first time), decoct 3 times, each decoction 1.0h, centrifuge at 16000r / min for 15min, The supernatant was mixed and concentrated until the crude drug content was 1g / ml, sodium benzoate was added in an amount of 1g / L, stirred evenly, and then aseptically filled.

Embodiment 2

[0065] The preparation of embodiment 2 oral liquid

[0066] The prescription medicinal materials per 1000ml liquid medicine are: Astragalus 400g, Angelica 300g, Epimedium 300g, Lycium barbarum 200g, Atractylodes 200g, Hawthorn 200g.

[0067] Add the above-mentioned six herbs to 10 times the amount of water that is 10 times the weight of the Chinese medicinal materials (considering the water absorption rate of the medicinal materials, add 2 times the amount of water for the first time), decoct 3 times, each decoction 1.0h, 16000r / min speed Centrifuge for 15min, concentrate the supernatant until the crude drug content is 1g / ml, add sodium benzoate in an amount of 1g / L, stir well, and aseptically fill.

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Abstract

The invention relates to a Chinese medicine composition with the function of immunological enhancement and application thereof. The Chinese medicine composition comprises the following Chinese medicines in parts by weight: 200-400 parts of Astragalus membranaceus, 100-300 parts of Chinese angelica, 100-300 parts of epimedium herb, 100-200 parts of Chinese wolfberry fruit, 100-200 parts of Chinese atractylode rhizome and 100-200 parts of hawthorns. Animal experiments prove that the Chinese medicine composition can obviously improve the cellular immunity function and the humoral immunity function of livestock and poultry to promote growth, obviously promote lymphopoiesis in vitro and has no toxicity and clinical application safety. The composition disclosed by the invention has the advantages of high efficiency, safety, quality controllability and the like.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and relates to a traditional Chinese medicine composition with immune enhancing effect and application thereof. The traditional Chinese medicine composition of the invention has the effect of enhancing immunity, and the traditional Chinese medicine oral liquid prepared from the traditional Chinese medicine composition is named Guiqiyin oral liquid, which belongs to a new type of immune enhancer for enhancing the immune function of livestock and poultry. Background technique [0002] Infectious diseases of livestock and poultry have always been the primary problem that endangers the development of animal husbandry, especially the major viral infectious diseases that are currently prevalent. So far, there is no effective treatment drug and program, which has caused huge economic losses to the breeding industry. In my country, the direct economic loss caused by animal epidemics is 26-30 b...

Claims

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Application Information

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IPC IPC(8): A61K36/815A61P37/04
Inventor 马兴旺刘俐君胡元亮杨德明王德云刘雁平邓学兵倪洪波张明玉张忠华闫宏光马丽刘建宋吉胜常兴友
Owner 南京日升昌生物技术有限公司
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