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Method for producing bee pollen tablets for treating premature ovarian failure of women

A technology for premature ovarian failure and bee pollen tablets, which is applied in the directions of medical raw materials derived from arthropods, sexual diseases, and pill delivery, etc., can solve the problems of reduced product activity titer, uneven quality, and low comprehensive processing and utilization level, etc. Retains the activity of functional substances, is not easy to oxidize and deteriorates, and is suitable for long-distance transportation

Inactive Publication Date: 2011-07-06
周斌 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In contrast, although the development and research of bee pollen in my country has been carried out for more than ten years, and a large number of bee pollen products have appeared, the level of comprehensive processing and utilization is not high. Not uniform, the degree of intensive processing is not high, export products are even rarer, and the precious resources of bee pollen have not been well utilized
[0007] However, due to the long-term storage of the traditionally collected freeze-dried powder of bee pollen water extract, it is easy to absorb moisture and regain moisture, resulting in product stickiness, which not only affects product quality, reduces product activity and potency, but also affects product consumption, which greatly affects product use.

Method used

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Examples

Experimental program
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Effect test

Embodiment Construction

[0019] 1. Prepare the freeze-dried powder of bee pollen aqueous extract for the treatment of premature ovarian failure in women:

[0020] 1. Sorting pollen: remove impurities in bee pollen at room temperature.

[0021] 2. Wall breaking: The impurity-removed bee pollen is broken under the frequency of the grading motor at 55-60Hz and the air source pressure at 0.7-1.0MPa.

[0022] 3. Soaking and ultrasonic treatment: Soak the broken bee pollen in water at normal pressure and temperature, and use ultrasonic treatment for 10 to 20 minutes.

[0023] 4. Impurity removal: Centrifuge the ultrasonically treated material in a refrigerated centrifuge with a rotational speed of 8,000 to 10,000 rpm for 8 to 12 minutes to remove solid impurities and take the supernatant.

[0024] 5. Ultrafiltration: Pass the supernatant through a molecular sieve below 4800D at an ambient temperature of -5 to 5°C to separate the water-soluble matter with a molecular weight less than 4800D, which is the bee...

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Abstract

The invention provides a method for producing bee pollen tablets for treating premature ovarian failure of women, relating to the technical field of production of tablet products. The method comprises the steps of: after pulverizing by air stream and wall-breaking treatment, immersing cleaned bee pollen in water with normal pressure and normal temperature; carrying out ultrasonication; centrifuging by a refrigerated centrifuger at a rotating speed of 8000-10000 revolutions; taking a supernate; separating a bee pollen water soluble substance with a molecular weight less than 4800D from the supernate at an ambient temperature of -5-5 DEG C; carrying out vacuum freeze drying on the bee pollen water soluble substance with a molecular weight less than 4800D to obtain lyophilized bee pollen with a water content less than 4%; and mixing the lyophilized bee pollen with water-soluble starch and preparing into tablets. The bee pollen tablets prepared by the method of the invention are used for treating premature ovarian failure of women by utilizing a bee pollen water soluble extract, and have the advantages of obvious effect, no side effect, low cost, simplicity, and practicability.

Description

technical field [0001] The invention relates to product tablet production technology, in particular to a tablet production method for treating premature ovarian failure in women. Background technique [0002] Tablets were developed on the basis of pills and were created in the 1840s. By the end of the 19th century, with the development of tablet presses, they were continuously improved, and the application of tablets developed rapidly. In the past ten years, tablet production technology and mechanical equipment have been greatly developed, such as boiling granulation, full powder direct compression, semi-film coating, etc. The research and production of Chinese medicine tablets began in the 1950s. With the comprehensive research of Chinese medicine chemistry, pharmacology, preparation and clinical aspects, the variety and quantity of Chinese medicine tablets continued to increase, and the technology improved day by day, and the quality of the tablets gradually increased. im...

Claims

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Application Information

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IPC IPC(8): A61K36/00A61K9/20A61P15/08A61K35/64A61K35/644
Inventor 周斌叶满红
Owner 周斌
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