Novel high-efficiency anticoccidial medicament decoquinate solution and preparation method thereof

Abstract

The invention relates to a novel high-efficiency anticoccidial medicament, namely decoquinate solution and a preparation method thereof. The medicament mainly overcomes the disadvantages of complicated production process, inconvenience of dosing, inaccurate dosage, low parasite dispelling effect and the like of the conventional premix medicament. The medicament comprises the following components: a primary medicament, namely decoquinate, dimethylformamide, ethanol, propylene glycol, Tween 80, 85 to 90 percent of cosolvent, and 4 to 9 percent of triethanolamine. The preparation method for the medicament comprises the following steps of: introducing the dimethylformamide, the ethanol and the propylene glycol into a liquid distribution tank, adding the decoquinate and the cosolvent according to a formula, heating for dissolution, naturally cooling, and adding the Tween 80 and the propylene glycol according to the formula, and mixing uniformly. The invention has the advantages that: the production process is simple; and the product is stable in quality, simple in dosing operation, and accurate in dosage, and is dosed by a quantitative dosing device.

Description

technical field [0001] The invention relates to a novel high-efficiency anticoccidial drug decoquinate solution and a preparation method thereof. Background technique [0002] Decyloxyquinate, the chemical name is 6-decyloxy-7-ethoxy-4-hydroxy-3-quinolinecarboxylic acid ethyl ester. This product is an anti-coccidial drug of the quinoline class, which is effective against a variety of Eimeria coccidia, and is used to prevent chicken balls caused by various coccidia (mutated, tender, giant, piled, poisonous, and Brucella, etc.) Bug disease. Since decoquinate has been used for a short time in my country, the range of use is small, and there is no drug resistance, it is an ideal new product for drug rotation. Decoxyquinate has excellent anti-coccidial effect and growth-promoting performance, and it starts to play a role in the early life cycle of coccidia, and can effectively protect the intestinal tract from coccidia. All have good results. The toxicity of decoquinate lasts...

AI Technical Summary

Problems solved by technology

[0005] 2. After chickens get sick, in most cases, the feed intake will decrease, but the drinking water will not be greatly affected. If the premix is ​​used, the blood drug concentration in the body will not reach the effective amount or the effective amount will be prolonged due to the small amount of food. time, delay in timely control of the disease, and drinking water administration will not be affected

[0006] 3. For most small and medium-sized farms, there is no drug premixing ability, and the drug premix cannot be evenly mixed into the full-price feed, resulting in local drug concentrations that are too high or too low, resulting in adverse consequences , decoquinate solution is easy to mix evenly

[0007] Decoxyquinate solution has not been reported or approved for application at home and abroad, and no patent protection has been found in patent searches