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Collagen oral liquid with improved bioavailability

A collagen oral liquid and collagen technology, which are applied in the field of oral liquid, can solve the problems of low collagen content, high molecular weight, unsatisfactory absorption by the human body, etc., and achieve the effects of improved bioavailability, stable quality and good taste.

Inactive Publication Date: 2011-06-01
上海中邦斯瑞生物药业技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these products have low collagen content and high molecular weight, so they are not ideal in terms of human absorption, and it is difficult to achieve the intended purpose

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Collagen 10g

[0025] Hypromellose 5g

[0026] Sucralose 5g

[0027] Benzoic acid 2g

[0028] Purified water dissolved to 100ml

[0029] Preparation: dissolving collagen and other substances in the prescription, stirring evenly to obtain a collagen mixture; filtering the obtained mixture with a polymer filter membrane, filling, sealing; microwave heating and sterilization; that is.

Embodiment 2

[0031] Collagen 12g

[0032] Sodium alginate 8g

[0033] Aspartame 6g

[0034] Sodium Benzoate 2.4g

[0035] Purified water dissolved to 100ml

[0036] Preparation: dissolving collagen and other substances in the prescription, stirring evenly to obtain a collagen mixture; filtering the obtained mixture with a polymer filter membrane, filling, sealing; microwave heating and sterilization; that is.

Embodiment 3

[0038] Collagen 15g

[0039] Sodium Carboxymethyl Cellulose 10g

[0040] Blueberry Extract 10g

[0041] Glucose 5g

[0042] Ethylparaben 2g

[0043] Purified water dissolved to 100ml

[0044]Preparation: dissolving collagen and other substances in the prescription, stirring evenly to obtain a collagen mixture; filtering the obtained mixture with a polymer filter membrane, filling, sealing; microwave heating and sterilization; that is.

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Abstract

The invention provides a collagen oral liquid with improved bioavailability, comprising bioabsorbable collagen and a stabilizer capable of promoting dispersion of the collagen. The collagen oral liquid provided by the invention contains higher content of the bioabsorbale collagen, wherein the molecular weight of the bioabsorbale collagen is from 2500D to 3500D and the content of the bioabsorbale collagen is no less than 10% (g / ml). The stabilizer capable of promoting dispersion of the collagen adopted by in the invention is selected from hydroxypropyl methyl cellulose (HPMC), sodium alginate, sodium carboxymethyl cellulose, methyl cellulose, xanthan gum and non-ionic surfactant, wherein the non-ionic surfactant contains aliphatic chains and the hydrophile-lipophile balance (HLB) value of the non-ionic surfactant is from 7 to 13. The collagen oral liquid provided in the invention is used to improve skin condition and prevent bone joint diseases.

Description

technical field [0001] The invention relates to an oral liquid, in particular to an oral liquid prepared from bioabsorbable collagen, which has the characteristics of high collagen content and high bioavailability after taking, and can be used to improve skin conditions and prevent and treat bone joints disease. Background technique [0002] Collagen is the main component of the skin. Collagen accounts for 72% of the skin and 80% of the dermis. It is widely distributed in connective tissue, skin, bone, interstitial cells of internal organs, muscle cavity, ligament, sclera, etc. parts. Collagen is an extremely important structural protein of connective tissue, which supports organs and protects the body, and is the main factor determining the toughness of connective tissue. Connective tissue binds cells throughout the body and connects them into organs and tissues, and has functions such as defense, support, protection, and nutrition. Collagen is closely related to various...

Claims

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Application Information

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IPC IPC(8): A61K9/08A61K38/39A61K47/38A61K47/36A61K47/34A61P17/00A61P19/02A61K36/45A61K31/375A61K31/4415A61K31/714
Inventor 王洪俊
Owner 上海中邦斯瑞生物药业技术有限公司
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