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Lycium ruthenicum Murr proanthocyanidin product and preparation method thereof

A technology of berry proanthocyanidins and black fruit Lycium barbarum is applied in the directions of pharmaceutical formulations, plant raw materials, medical preparations containing active ingredients, etc. The effect of stable nature and simple process

Active Publication Date: 2011-03-02
浙江启润生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the preparation of proanthocyanidins is mostly extracted by organic reagents, which is energy-consuming, time-consuming, costly, and toxic, and is not suitable for industrial production.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Example 1 A proanthocyanidin product from Lycium barbarum is a lavender powder, wherein the content of oligomeric proanthocyanidins is 55%, the content of high polymer proanthocyanidins is 10%, and other impurities are 35%.

[0021] The preparation method of this proanthocyanidin product of black fruit wolfberry comprises the following steps:

[0022] (1) Squeeze 100kg of fresh wolfberry black fruit into juice with a juice extractor.

[0023] (2) Under the conditions of a pressure of 0.005MPa, a temperature of 15°C, and a flow rate of 1ml / min, the juice is removed by a ceramic membrane with a pore size of 0.1um to remove suspended solids, tannin and mucus in the juice, Obtain filtrate.

[0024] (3) Pass the filtrate through a non-polar macroporous adsorption resin, first elute with deionized water until sugar-free, and then elute with an ethanol solution with 2 times the column volume and a mass concentration of 40%, to obtain the eluate containing proanthocyanidins l...

Embodiment 2

[0028] Example 2 A proanthocyanidin product of Lycium barbarum is a lavender powder, wherein the content of oligomeric proanthocyanidins is 50%, the content of high polymer proanthocyanidins is 15%, and other impurities are 35%.

[0029] The preparation method of this proanthocyanidin product of black fruit wolfberry comprises the following steps:

[0030] (1) Squeeze 100kg of fresh wolfberry black fruit into juice with a juice extractor.

[0031] (2) Under the conditions of a pressure of 3Mpa, a temperature of 45°C, and a flow rate of 300ml / min, after the juice is removed by a ceramic membrane with a pore size of 10um, the suspended solids, tannin and mucilage in the juice are removed, and the filtered liquid.

[0032] (3) The filtrate is passed through a nonpolar macroporous adsorption resin, first eluted with deionized water to sugar-free, and then eluted with 50 times of column volume and anhydrous (mass concentration is 100%) ethanol solution to obtain The eluate of pro...

Embodiment 3

[0036] Example 3 A proanthocyanidin product of Lycium barbarum is a lavender powder, wherein the content of oligomeric proanthocyanidins is 40%, the content of high polymer proanthocyanidins is 20%, and other impurities are 40%.

[0037] The preparation method of this proanthocyanidin product of black fruit wolfberry comprises the following steps:

[0038] (1) Squeeze 100kg of fresh wolfberry black fruit into juice with a juice extractor.

[0039] (2) Under the conditions of a pressure of 0.01Mpa, a temperature of 20°C, and a flow rate of 15ml / min, the juice is removed by a ceramic membrane with a pore size of 2um to remove suspended solids, tannin and mucus in the juice to obtain filtrate.

[0040] (3) Pass the filtrate through a non-polar macroporous adsorption resin, first elute with deionized water until sugar-free, and then elute with 20 times the column volume and an ethanol solution with a mass concentration of 50%, to obtain the eluate containing proanthocyanidins li...

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PUM

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Abstract

The invention relates to a lycium ruthenicum Murr proanthocyanidin product. The product is a pale purple pink powder product which is prepared from fresh lycium ruthenicum Murr as raw materials and contains 40% to 70% of oligomeric proanthocyanidins, 10% to 35% of high polymer procyanidins, and 10% to 40% of other impurities after being separated and purified. The invention also discloses a preparation method of the product. The invention adopts the membrane separation technique, has simple and quick method, not only avoids using toxicant organic reagent and acquires the product having stable and uniform property, but also efficiently lowers the producing cost and can adopt the raw materials of health care product which has an antioxidant function.

Description

technical field [0001] The invention relates to a proanthocyanidin product and a preparation method thereof, in particular to a proanthocyanidin product of black fruit wolfberry and a preparation method thereof. Background technique [0002] Proanthocyanidin, or OPC for short, is a bioflavonoid with a special molecular structure, soluble in water and most organic solvents, and has efficient anti-aging, anti-cardiovascular disease, and anti-cancer functions. Fatigue, improve memory and other effects, showing incomparably superior biological activity and safety. Lycium ruthenicum Murr. is a plant of the genus Lycium ruthenicum Murr. It is a common wild shrub in some parts of Northwest my country. Its berries are round and black-purple when ripe. %, the proanthocyanidin content of the dried fruit is 7.2%, which has a good market development prospect. [0003] At present, the preparation of proanthocyanidin products mostly adopts the extraction of organic reagents, which is ene...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/815A61P39/06A61K131/00
Inventor 赵晓辉陈涛陶燕铎陈桂琛梅丽娟李玉林邵赟
Owner 浙江启润生物科技有限公司
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