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Medicinal composition for curing gynecological diseases and preparation method thereof

A technology for gynecological diseases and compositions, which is applied in the field of pharmaceutical compositions for treating gynecological diseases and its preparation, can solve the problems of difficult implementation of metal treatment methods, low cure rate of Aibao therapy, and high price of interferon, etc., to avoid gastrointestinal Physiological checkpoint effect, satisfactory curative effect, avoiding liver first-pass effect

Inactive Publication Date: 2010-09-22
北京康正元科技发展有限公司武汉分公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The following problems exist in the treatment of patients with cervical erosion and intrauterine devices: most of the intrauterine devices contain metal, and the conductivity of metal makes the treatment difficult to implement
However, interferon is expensive and has many side effects, which is a bottleneck that limits its wide application
②Aibo Therapy The main component of Aibao Therapy is polycresol, but the cure rate of Aibao Therapy is low and the course of treatment is long
But there are also the disadvantages that most of the clinical medicines are decoctions and inconvenient to take.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031]Phellodendron 400g, Agrimony 400g, Cnidium 400g, Senecio 400g, dry alum 300g, borneol 100g; dry alum crushed into fine powder, add 10 times water to decoct Phellodendron, Agrimony, Cnidium, Senecio 3 times, the first 2 hours for the first time, 1 hour for the second time, 1 hour for the third time, combine the decoction, filter, concentrate the filtrate to an appropriate amount, add ethanol to make the alcohol content in the solution 75%, stir, let stand for 24 hours, take the supernatant Ethanol is recovered from the liquid, concentrated into a thick paste with a relative density of 1.3 to 1.35 (25 to 30°C), dried in vacuum, and the dry paste is crushed into fine powder, mixed with dry alum fine powder and crospovidone; use 60% ethanol To make soft material, granulate with a 20-mesh sieve, dry, and granulate; spray dry granules into absolute ethanol dissolved in borneol, mix well, seal, add appropriate amount of crospovidone, compress into tablets, and make 1000 vaginal ...

Embodiment 2

[0033] Phellodendron 250, Agrimony 450, Cnidium 450, Senecio 600, Alum 150, Borneol 100; Step 1: Add 10 times water to decoct Phellodendron, Agrimony, Cnidium, and Senecio for 3 times, the first time for 2 hours, 1 hour for the second time, 1 hour for the third time, combine the decoction, filter, concentrate the filtrate to an appropriate amount, add ethanol to make the alcohol content in the solution 75%, stir, let stand for 24 hours, take the supernatant to recover ethanol, Concentrate into a thick paste with a relative density of 1.3-1.35 (25-30°C), add xylitol to the thick paste, stir and mix, dry under reduced pressure at 60 degrees, and set aside;

[0034] Step 2: crush the dry alum into fine powder for subsequent use;

[0035] Step 3: Dry the boric acid and the effervescent agent at 105 degrees respectively for later use;

[0036] Step 4: Dissolve the borneol with an appropriate amount of absolute ethanol and set aside;

[0037] Step 5: Crush the spare parts of steps...

Embodiment 3

[0039] Phellodendron 700, Agrimony 250, Cnidium 200, Senecio 600, Dry alum 200, Borneol 50; Dry alum crushed into fine powder, Phellodendron, Agrimony, Cnidium, Senecio plus 10 times water decoction 3 times, the first 2 hours for the first time, 1 hour for the second time, 1 hour for the third time, combine the decoction, filter, concentrate the filtrate to an appropriate amount, add ethanol to make the alcohol content in the solution 75%, stir, let stand for 24 hours, take the supernatant Ethanol is recovered from the liquid, concentrated into a thick paste with a relative density of 1.3 to 1.35 (25 to 30°C), mixed with dry alum fine powder, added to a matrix made of polyoxyethylene monofatty acid ester and glycerin, mixed evenly, poured Mold, cool, demould, make 1000 suppositories.

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PUM

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Abstract

The invention discloses a Chinese medicinal external composition for curing gynecological diseases and a preparation method thereof. The composition is prepared from amur corktree bark, hairyvein agrimonia herb and bud, common cnidium fruit, climbing groundsel herb, dried alum and borneol in a certain ratio. The composition is prepared into clinically acceptable external formulations such as suppository, external capsules, gel, ointments, vaginal tablets, vaginal effervescent tablets, vaginal films, lotion, aerosol, foaming agent and the like by a pharmaceutical conventional method. The composition has good curative effects on cervical erosion, gynecological inflammation, and urinary tract infection of women. The composition is prepared into an external preparation and is not orally administrated so as to avoid first-pass effect on liver and physiological screening effects of gastrointestinal tracts and reduce untoward effect. The external preparation can directly act on afflicted parts, and has the advantages of strong pertinence, general actions through skin and mucosa, quick medicinal absorption, less interference to internal environment of body, non-traumatic treatment mode, simple operation, good safety of clinical use, high cure rate, base strengthening of Chinese medicaments, and less side effect. The composition can effectively eliminate cause of diseases, can safely and effectively cure diseases under guidance of doctors and is easy to popularize.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating gynecological diseases and a preparation method thereof, in particular to an external Chinese medicine composition for treating pelvic inflammatory disease, vaginitis, cervicitis, cervical erosion and urinary tract infection and a preparation method thereof and uses. Background technique [0002] Cervical erosion is the most common genital inflammation in women, more common in married women. Chinese medical workers conducted an epidemiological survey in a city in Hubei, and found that the incidence of cervical erosion among working married women was as high as 43.89%, among which 70.12% were mild cervical erosion and 27.86% were moderate cervical erosion. %, severe cervical erosion accounted for 2.02%. In terms of classification, the simple type accounted for the majority, accounting for 56.69%, and the mastoid and granular types accounted for 43.31%; the incidence rate of rural women...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61P15/00A61P13/00A61K31/045A61K33/06
Inventor 邵振军
Owner 北京康正元科技发展有限公司武汉分公司
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