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Electrostatic spinning device

A technology of electrospinning and spinning devices, which is applied in the field of electrospinning polymer electrospun fibers prepared by electrospinning technology, which can solve the problems of hindering deposition and waste, and achieve the effects of pain relief, simple operation and convenient removal

Inactive Publication Date: 2010-09-15
ZHEJIANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This results in a certain deposition of material outside the target area which is wasteful
At the same time, because the fibers will be attracted by the electric field and preferentially deposited in the part of the wound close to the electrospinning equipment, the fibers will be hindered by the electric field from being effectively deposited in the depth of scratches or other wounds

Method used

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  • Electrostatic spinning device
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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0075] Medical dressings are prepared using fibers containing polycaprolactone and / or linear polyethyleneimine.

[0076] Polycaprolactone was dissolved in acetone to prepare an 18% (w / w) solution. A 25% (w / w) solution was prepared by dissolving linear polyethyleneimine in ethanol. Samples were prepared by mixing the above solutions. And use a variety of pH adjusters. When alginic acid or Carbopol is used, its mass fraction in the two polymers (polycaprolactone / linear polyethyleneimine) is 2.9% or its mass fraction in the polymer solution (polycaprolactone / linear polyethyleneimine ) at a concentration of 2.9% (w / w) In order to mix the pH adjuster, alginic acid was first dissolved in a small amount of ethanol, followed by a linear polyethyleneimine solution and finally a polycaprolactone solution. The final mixture is immediately spun through the above-mentioned electrospinning device 1 to avoid the aggregation of the pH regulator, and to obtain a medical composite, that is, ...

Embodiment 2

[0102] Fibers are prepared from various composite polymer solutions by adding therapeutic components to the raw material solution.

[0103] Prepare polycaprolactone (PCL) solution, polyhydroxyethylmethacrylate (Poly-HEMA) solution, polyvinylpyrrolidone (PVP) solution, polyethyloxazoline (PEOz) solution, polyoxyethylene (PEO) solution, And linear polyethyleneimine (L-PEI) solution, by adding different therapeutic components to it, forming a variety of composite polymer solutions to make fibers.

[0104] When preparing polycaprolactone (PCL) solution, first add 12.29g polycaprolactone (PCL) and 50g acetone in the beaker, heat until dissolving, after the polymer dissolves, the solution is stirred and cooled to room temperature, then in the sample Add acetone to make the mass percent concentration of polycaprolactone (PCL) in acetone reach 16%.

[0105] When preparing polyethyloxazoline (PEOz), polyoxyethylene (PEO), and polyvinylpyrrolidone (PVP) solutions, take the same steps a...

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Abstract

The invention discloses an electrostatic spinning device, comprising a liquid storage pot, a power supply and a spinning device, wherein, the liquid storage pot is provided with a liquid inlet and a liquid outlet, the power supply is connected with the liquid storage pot by a circuit, the spinning device is communicated with the liquid outlet of the liquid storage pot, and the anode of the power supply is connected with the liquid storage pot and the spinning device by a lead wire. The device can take a wound as a receiving device while preparing polymer electrospun fiber by electrostatic spinning and directly forms a film on the wound to obtain a medical compound; and the obtained compound can be directly applied to the surface of the wound and stably covers the wound.

Description

technical field [0001] The invention relates to the technical field of preparing polymer electrostatic spinning fibers by adopting electrostatic spinning technology, in particular to a polymer electrostatic spinning device. Background technique [0002] There have been some patent reports and laboratory studies on electrospinning technology. In the process of electrospinning, an electric field is first formed on the surface of the liquid, and when the force of the electric field acts on the surface of the liquid, a charged liquid jet will be generated on the surface of the liquid. A liquid jet is stretched by being attracted to oppositely charged substances with the right electrical potential. As the liquid jet is stretched, it dries and solidifies, creating fibers. The stretched liquid jet can be solidified and dried by physical solidification such as cooling of the liquid, evaporation of the solvent, or by chemical solidification. The generated fibers are collected by a...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): D01D5/00D01D13/00D01F1/10A61L15/22
Inventor 孙朝辉胡杰霍平张林
Owner ZHEJIANG UNIV
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